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Prednisone is a glucocorticoid medication mostly used to suppress the immune system and decrease inflammation in conditions such as asthma, COPD, and rheumatologic diseases. [3] It is also used to treat high blood calcium due to cancer and adrenal insufficiency along with other steroids. [3] It is taken by mouth. [3]
To prevent steroid-induced osteoporosis, the steroid dose and duration should be as low and as short as possible. All patients on long term glucocorticoids (≥3 months) should be encouraged to do weightbearing exercise, avoid smoking and excess alcohol and take fall prevention measures. Daily calcium and vitamin d intake should be sufficient.
AS always with all drugs, and particularly yes with this one if you are on a long term prescription. Prednisone because of its side effects is typically and ideally only given for weeks or a few months. The higher the dose the truer this is. 10mg a day is a moderate dose, 50mg a day is a high one.
Initial treatment is usually with oral prednisone (50–150 mg/day) or high-dose intravenous methylprednisolone (1 g/day) for 3–7 days. Thyroid hormone treatment is also included if required. Thyroid hormone treatment is also included if required.
Methylprednisolone (Depo-Medrol, Medrol, Solu-Medrol) is a synthetic glucocorticoid, primarily prescribed for its anti-inflammatory and immunosuppressive effects. [4] [5] [6] It is either used at low doses for chronic illnesses or used concomitantly at high doses during acute flares.
In a prospective study, the cumulative incidence of CIL with high-dose prednisone therapy was found to be 61% after 3 months, 65% after 6 months, 68% after 9 months, and 69% after 12 months. [1] One study found that even a very low dosage of prednisone of 5 mg/day was associated with symptoms of "Cushing's syndrome". [1]
Vitamin D supplementation could interact with some medications such as a statin (cholesterol reducing medication), orlistat (a weight loss drug), steroids (such as prednisone), and some types of ...
Because high-dose prednisone rapidly lowers eosinophil levels, it is usually started at a dose of 1 mg/kg/day. [6] Upon achieving appropriate control over eosinophilia, the medication can be gradually reduced. [25] Steroid-refractory HES has been managed with a variety of cytotoxic treatments. [24]