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Of the drugs that cause DIL, hydralazine has been found to cause a higher incidence. Hydralazine is a medication used to treat high blood pressure. Approximately 5% of the patients who have taken hydralazine over long periods of time and in high doses have shown DIL-like symptoms. [8] Many of the other drugs have a low to very low risk to ...
Second is a discoid rash, which is chronic rash in sun-exposed areas that are plaque-like or forms a sort of patchy redness and can scar. Finally, a general photosensitivity of the skin—essentially a catch-all category for other rashes that happen to sun-exposed areas—typically only lasting a couple of days.
Prolonged treatment may cause a syndrome similar to lupus, which can become fatal if the symptoms are not noticed and drug treatment stopped. [13] Hydralazine is within the top three drugs that is known to induce systemic lupus and this adverse drug event is dose dependent yet significant.
The modern period, beginning in 1920, saw major developments in research into the cause and treatment of discoid and systemic lupus. Research conducted in the 1920s and 1930s led to the first detailed pathologic descriptions of lupus and demonstrated how the disease affected the kidney, heart, and lung tissue. [ 165 ]
Lupus erythematosus is a collection of autoimmune diseases in which the human immune system becomes hyperactive and attacks healthy tissues. [1] Symptoms of these diseases can affect many different body systems, including joints, skin, kidneys, blood cells, heart, and lungs.
Toni Braxton opened up about the long road to getting a lupus diagnosis, and why she didn’t initially go public about the autoimmune disease. “I worked hard to hide it for the longest time ...
After about three months, I got a rash all over my legs. I had horrible cramping in my stomach, was exhausted all the time, and I would wake up in the middle of the night drenched in sweat ...
A malar rash (from Latin mala 'jaw, cheek-bone'), also called butterfly rash, [1] is a medical sign consisting of a characteristic form of facial rash. It is often seen in lupus erythematosus. More rarely, it is also seen in other diseases, such as pellagra, dermatomyositis, and Bloom syndrome. There are many conditions which can cause rashes ...