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To maintain blood levels of calcium, therapeutic vitamin D doses are sometimes administered (up to 100 000 IU or 2.5 mg daily) to patients who have had their parathyroid glands removed (most commonly kidney dialysis patients who have had tertiary hyperparathyroidism, but also to patients with primary hyperparathyroidism) or with ...
The Institute of Medicine in 2010 recommended a maximum uptake of vitamin D of 4000 IU/d, finding that the dose for lowest observed adverse effect level is 40,000 IU daily for at least 12 weeks, [25] and that there was a single case of toxicity above 10 000 IU after more than seven years of daily intake; this case of toxicity occurred in ...
It is rare, having occurred historically during a time of unregulated fortification of foods, especially those provided to infants, [5]: 431–432 or in more recently, with consumption of high-dose vitamin D dietary supplements following inappropriate prescribing, non-prescribed consumption of high-dose, over-the-counter preparations, or ...
Signs of vitamin D deficiency. Fatigue. Mood changes. Muscle pain and weakness. Reduced immune function. Increased inflammation. Frequent infections. Rickets (in children)
Since vitamin D is a fat-soluble vitamin, too much can put you at serious risk for toxicity including adverse side effects like kidney stones and high calcium levels in the blood.
With the vitamin D deficiency resurfacing the nutrient reference value guidelines were established, in turn creating the dietary vitamin D recommendations. [2] The dietary vitamin D guidelines are assuming limited exposure to UVB sunlight are: Infants, Children and Adults < 50 years: 5 μg/day (200 IU/day)
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