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  2. Pantothenate kinase-associated neurodegeneration - Wikipedia

    en.wikipedia.org/wiki/Pantothenate_kinase...

    PANK2 encodes a 1.85Kb transcript which is derived from seven exons covering a total distance of approximately 3.5Mb of genomic DNA. The PANK2 gene also encodes a 50.5-kDa protein that is a functional pantothenate kinase , an essential regulatory enzyme in coenzyme A (CoA) biosynthesis, and catalyzing the phosphorylation of pantothenate ...

  3. Iron in biology - Wikipedia

    en.wikipedia.org/wiki/Iron_in_biology

    Iron can be stored in ferritin as ferric iron due to the ferroxidase activity of the ferritin heavy chain. [43] Dysfunctional ferritin may accumulate as hemosiderin, which can be problematic in cases of iron overload. [44] The ferritin storage iron pool is much larger than the labile iron pool, ranging in concentration from 0.7 mM to 3.6 mM. [40]

  4. While it does contain more iron than many vegetables such as asparagus, Swiss chard, kale, or arugula, it contains only about one-third to one-fifth of the iron in lima beans, chickpeas, apricots, or wheat germ. Additionally, the non-heme iron found in spinach and other vegetables is not as readily absorbed as the heme iron found in meats and fish.

  5. Human iron metabolism - Wikipedia

    en.wikipedia.org/wiki/Human_iron_metabolism

    Iron can be stored in ferritin as ferric iron due to the ferroxidase activity of the ferritin heavy chain. [28] Dysfunctional ferritin may accumulate as hemosiderin, which can be problematic in cases of iron overload. [29] The ferritin storage iron pool is much larger than the labile iron pool, ranging in concentration from 0.7 mM to 3.6 mM. [25]

  6. Iron overload - Wikipedia

    en.wikipedia.org/wiki/Iron_overload

    Iron overload (also known as haemochromatosis or hemochromatosis) is the abnormal and increased accumulation of total iron in the body, leading to organ damage. [1] The primary mechanism of organ damage is oxidative stress, as elevated intracellular iron levels increase free radical formation via the Fenton reaction.

  7. Nutritional neuroscience - Wikipedia

    en.wikipedia.org/wiki/Nutritional_neuroscience

    Poor diet in early childhood affects the number of neurons in parts of the brain. [1]Nutritional neuroscience is the scientific discipline that studies the effects various components of the diet such as minerals, vitamins, protein, carbohydrates, fats, dietary supplements, synthetic hormones, and food additives have on neurochemistry, neurobiology, behavior, and cognition.

  8. Biometal (biology) - Wikipedia

    en.wikipedia.org/wiki/Biometal_(biology)

    Iron is also the most abundant transition metal in the human body and it is used in various processes like oxygen transport and ATP production. It plays a key role in the function of enzymes like cytochrome a , b and c as well as iron-sulfur complexes which play an important role in ATP production. [ 13 ]

  9. Handicap principle - Wikipedia

    en.wikipedia.org/wiki/Handicap_principle

    The handicap principle is a disputed hypothesis proposed by the Israeli biologist Amotz Zahavi in 1975. It is meant to explain how "signal selection" during mate choice may lead to "honest" or reliable signalling between male and female animals which have an obvious motivation to bluff or deceive each other.