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  2. Erythropoiesis - Wikipedia

    en.wikipedia.org/wiki/Erythropoiesis

    A feedback loop involving erythropoietin helps regulate the process of erythropoiesis so that, in non-disease states, the production of red blood cells is equal to the destruction of red blood cells and the red blood cell number is sufficient to sustain adequate tissue oxygen levels but not so high as to cause sludging, thrombosis, or stroke ...

  3. Red blood cell - Wikipedia

    en.wikipedia.org/wiki/Red_blood_cell

    Red blood cells (RBCs), referred to as erythrocytes (from Ancient Greek erythros ' red ' and kytos ' hollow vessel ', with -cyte translated as 'cell' in modern usage) in academia and medical publishing, also known as red cells, [1] erythroid cells, and rarely haematids, are the most common type of blood cell and the vertebrate's principal means of delivering oxygen (O 2) to the body tissues ...

  4. Erythropoietin - Wikipedia

    en.wikipedia.org/wiki/Erythropoietin

    Erythropoietin is an essential hormone for red blood cell production. Without it, definitive erythropoiesis does not take place. Under hypoxic conditions, the kidney will produce and secrete erythropoietin to increase the production of red blood cells by targeting CFU-E , pro erythroblast and basophilic erythroblast subsets in the differentiation.

  5. Human iron metabolism - Wikipedia

    en.wikipedia.org/wiki/Human_iron_metabolism

    Heme iron in animals is from blood and heme-containing proteins in meat and mitochondria, whereas in plants, heme iron is present in mitochondria in all cells that use oxygen for respiration. Like most mineral nutrients, the majority of the iron absorbed from digested food or supplements is absorbed in the duodenum by enterocytes of the ...

  6. Iron in biology - Wikipedia

    en.wikipedia.org/wiki/Iron_in_biology

    Illustration of blood cell production in the bone marrow. In iron deficiency , the bone marrow produces fewer blood cells, and as the deficiency gets worse, the cells become smaller. Most well-nourished people in industrialized countries have 4 to 5 grams of iron in their bodies (~38 mg iron/kg body weight for women and ~50 mg iron/kg body for ...

  7. Blood cell - Wikipedia

    en.wikipedia.org/wiki/Blood_cell

    Hemoglobin is an iron-containing protein that gives red blood cells their color and facilitates transportation of oxygen from the lungs to tissues and carbon dioxide from tissues to the lungs to be exhaled. [3] Red blood cells are the most abundant cell in the blood, accounting for about 40–45% of its volume. Red blood cells are circular ...

  8. Hemoglobin - Wikipedia

    en.wikipedia.org/wiki/Hemoglobin

    Hemoglobin in normal red blood cells is protected by a reduction system to keep this from happening. Nitric oxide is capable of converting a small fraction of hemoglobin to methemoglobin in red blood cells. The latter reaction is a remnant activity of the more ancient nitric oxide dioxygenase function of globins.

  9. Blood - Wikipedia

    en.wikipedia.org/wiki/Blood

    The formed elements are the two types of blood cell or corpuscle – the red blood cells, (erythrocytes) and white blood cells (leukocytes), and the cell fragments called platelets [12] that are involved in clotting. By volume, the red blood cells constitute about 45% of whole blood, the plasma about 54.3%, and white cells about 0.7%.