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Neuroleptic malignant syndrome (NMS) is a rare [5] [6] but life-threatening reaction that can occur in response to antipsychotics (neuroleptic) or other drugs that block the effects of dopamine. [ 1 ] [ 7 ] Symptoms include high fever , confusion, rigid muscles, variable blood pressure, sweating, and fast heart rate. [ 1 ]
A large meta-analysis of 38 trials of antipsychotic drugs in schizophrenia with acute psychotic episodes showed an effect size of about 0.5. [37] There is little or no difference in efficacy among approved antipsychotic drugs, including both first- and second-generation agents. [23] [38] The efficacy of such drugs is suboptimal. Few patients ...
This is a general list of long-term side effects associated with Antipsychotic (neuroleptic) medication. Many patients will not develop these side effects, although there is still a significant possibility of risks associated with Antipsychotic usage.
1.1 Antipsychotic esters. 1.1.1 Typical antipsychotics. ... Antipsychotics by class Generic name Brand names Chemical class ATC code Typical antipsychotics; Acepromazine:
Certain medications such as dopamine agonists are not used, as they may worsen psychotic symptoms to those taking neuroleptic drugs. If the EPS are induced by an antipsychotic , EPS may be reduced by decreasing the dose of the antipsychotic or by switching from a typical antipsychotic to an (or to a different) atypical antipsychotic , such as ...
Neuroleptic malignant syndrome (NMS) is a rare, but potentially fatal side effect of antipsychotic treatment. NMS is characterized by fever, muscle rigidity, autonomic dysfunction, and altered mental status. Treatment includes discontinuation of the offending agent and supportive care.
Neuroleptic malignant syndrome a potentially fatal complication of antipsychotic drug treatment. Presents with hyperthermia, tremor, tachycardia (high heart rate), mental status change (e.g. confusion), etc.
Neuroleptic malignant syndrome, a potentially fatal complication of antipsychotic drug use. It is characterised by the following symptoms: Muscle rigidity; Tremors; Mental status change (e.g., hallucinations, agitation, stupor, confusion, etc.) Hyperthermia