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The RNA world hypothesis places RNA at center-stage when life originated. The RNA world hypothesis is supported by the observations that ribosomes are ribozymes: [120] [121] the catalytic site is composed of RNA, and proteins hold no major structural role and are of peripheral functional importance. This was confirmed with the deciphering of ...
Woese's dogma is a principle of evolutionary biology first put forth by biophysicist Carl Woese in 1977. It states that the evolution of ribosomal RNA was a necessary precursor to the evolution of modern life forms. [1]
These enclosed structures may have facilitated natural selection in RNA molecules. Under the pre-cell theory (Kandler 1994ff) [6] [7] [8], based on the Iron-Sulfur world hypothesis (metabolism-first scenario), [9] primordial metabolism led to the early diversification of life through the evolution of a multiphenotypical population of pre-cells ...
This difference between protein and ribonucleoprotein catalysts can be explained by extending the RNA world theory. The older RNA molecules were originally self-catalyzed through ribozymes, which evolved the assistance of proteins to form RNP. Thereafter, the newer DNA molecule used only the more efficient protein processes from the start. Thus ...
Kandler's pre-cell theory is supported by Wächtershäuser. [64] [65] In 1998, Carl Woese, based on the RNA world concept, proposed that no individual organism could be considered a LUCA, and that the genetic heritage of all modern organisms derived through horizontal gene transfer among an ancient community of organisms. [66]
Independent replicators (probably RNA) Chromosomes: RNA world hypothesis: RNA as both genes and enzymes: DNA as genes; proteins as enzymes Prokaryotes: Eukaryotes: Can observe [clarification needed] Asexual clones: Sexual populations: Evolution of sex: Protists: Multicellular organisms — animals, plants, fungi: Evolution of multicellularity ...
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One major shift is believed to be from the RNA world to an RNA-DNA-protein world. Modern phylogenies provide more pertinent genetic evidence about LUCA than about its precursors. [215] The most popular hypotheses for settings for the origin of life are deep sea hydrothermal vents and surface bodies of water.