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Their new text was first published in 1941 under the title The Pharmacological Basis of Therapeutics: A Textbook of Pharmacology, Toxicology and Therapeutics for Physicians and Medical Student. [1] Because the volume was twice as long as a typical textbook, Macmillan printed few copies, but demand for a readable, up-to-date pharmacological text ...
Pharmacology is the science of drugs and medications, [1] including a substance's origin, composition, pharmacokinetics, pharmacodynamics, therapeutic use, and toxicology. More specifically, it is the study of the interactions that occur between a living organism and chemicals that affect normal or abnormal biochemical function. [ 2 ]
The IUPHAR/BPS Guide to PHARMACOLOGY is an open-access website, acting as a portal to information on the biological targets of licensed drugs and other small molecules. The Guide to PHARMACOLOGY (with GtoPdb being the standard abbreviation) is developed as a joint venture between the International Union of Basic and Clinical Pharmacology (IUPHAR) and the British Pharmacological Society (BPS).
Molecular pharmacology – the discipline of studying drug actions at the molecular level; it is a branch of pharmacology in general. Pharmacogenomics – the study of the human genome in order to understand the ways in which genetic factors determine the actions of medicines.
The first pharmacokinetic model described in the scientific literature [2] was in fact a PBPK model. It led, however, to computations intractable at that time. The focus shifted then to simpler models, [3] for which analytical solutions could be obtained (such solutions were sums of exponential terms, which led to further simplifications.)
In pharmacology, the area under the plot of plasma concentration of a drug versus time after dosage (called “area under the curve” or AUC) gives insight into the extent of exposure to a drug and its clearance rate from the body.
As of 2023, Annual Review of Pharmacology and Toxicology is being published as open access, under the Subscribe to Open model. [1] As of 2024, Journal Citation Reports lists the journal's 2023 impact factor as 11.2, ranking it second of 106 journal titles in the category "Toxicology" and ninth of 354 titles in the category "Pharmacology ...
A sister journal, also published for the British Pharmacological Society by Wiley-Blackwell is the British Journal of Clinical Pharmacology. The journal publishes research papers, review articles, commentaries and correspondence in all fields of pharmacology. It also publishes themed issues, as well as supplements.