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Afterhyperpolarization, or AHP, is the hyperpolarizing phase of a neuron's action potential where the cell's membrane potential falls below the normal resting potential. This is also commonly referred to as an action potential's undershoot phase. AHPs have been segregated into "fast", "medium", and "slow" components that appear to have distinct ...
Slow afterhyperpolarisation (sAHP) refers to prolonged periods of hyperpolarisation in a neuron or cardiomyocyte following an action potential or other depolarising event. In neurons, trains of action potentials may be required to induce sAHPs; this is unlike fast AHPs that require no more than a single action potential.
[5] This process of hyperpolarization is highly dependent on which direction Cl – flows. If Cl – travels into the cell, the flow of ions increases the voltage gradient. If Cl – flows out of the cell, the voltage gradient will decrease. GABA B induces hyperpolarization through K + ion influx into the neuron.
After an action potential has occurred, there is a transient negative shift, called the afterhyperpolarization. In animal cells, there are two primary types of action potentials. One type is generated by voltage-gated sodium channels, the other by voltage-gated calcium channels. Sodium-based action potentials usually last for under one ...
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When the membrane's voltage becomes low enough, the inactivation gate reopens and the activation gate closes in a process called deinactivation. With the activation gate closed and the inactivation gate open, the Na + channel is once again in its deactivated state, and is ready to participate in another action potential.
140492 Ensembl ENSG00000080709 ENSMUSG00000054477 UniProt Q9H2S1 P58390 RefSeq (mRNA) NM_001278204 NM_021614 NM_170775 NM_001372233 NM_080465 NM_001312905 RefSeq (protein) NP_001265133 NP_067627 NP_740721 NP_001359162 NP_001299834 NP_536713 Location (UCSC) Chr 5: 114.06 – 114.5 Mb Chr 18: 45.27 – 45.69 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Potassium intermediate/small ...
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