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Drusen, from the German word for node or geode (singular, "Druse"), are tiny yellow or white accumulations of extracellular material that build up between Bruch's membrane and the retinal pigment epithelium of the eye. The presence of a few small ("hard") drusen is normal with advancing age, and most people over 40 have some hard drusen. [1]
Choroidal nevus with drusen can be considered as a sign of chronicity since drusen take years to develop and appear. [14] Drusen are composed of lipids and can actually be an indicator that a tumour is a benign nevus as opposed to a cancerous melanoma. [15] In nevi imaged by OCT, about 41% are found to have drusen. [16]
In children, optic disc drusen are usually buried and undetectable by fundoscopy except for a mild or moderate elevation of the optic disc. With age, the overlying axons become atrophied and the drusen become exposed and more visible. They may become apparent with an ophthalmoscope and some visual field loss at the end of adolescence. [7]
Druse can refer to: Druze or Durzi, a Middle Eastern religious community; Druse (botany), an aggregation of calcium oxalate crystals found in certain plants; Druse (geology), an incrustation of small crystals on the surface of a rock or mineral; Drusen, pathological deposits in the eye
Papilledema or papilloedema is optic disc swelling that is caused by increased intracranial pressure due to any cause. [1] The swelling is usually bilateral and can occur over a period of hours to weeks. [2] Unilateral presentation is extremely rare. In intracranial hypertension, the optic disc swelling most commonly occurs bilaterally.
Kris Jenner opened up about preparing to have her ovaries removed — and it doesn't seem like her health issues stop there. During the Thursday, July 4, episode of The Kardashians, Kris, 68, sat ...
Micrograph of heart muscle showing lipofuscin pigment, H&E stain. Lipofuscin accumulation in the eye, is a major risk factor implicated in macular degeneration, a degenerative disease, [15] and Stargardt disease, an inherited juvenile form of macular degeneration.
A druse is a group of crystals of calcium oxalate, [1] silicates, or carbonates present in plants, and are thought to be a defense against herbivory due to their toxicity. Calcium oxalate (Ca(COO) 2 , CaOx) crystals are found in algae , angiosperms and gymnosperms in more than 215 families.