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scVelo is a method that solves the full transcriptional dynamics of splicing kinetics using a likelihood-based dynamical model. This generalizes RNA velocity to systems with transient cell states, which are common in development and in response to perturbations. scVelo was applied to disentangling subpopulation kinetics in neurogenesis and pancreatic endocrinogenesis. scVelo demonstrate the ...
The Illinois long-term selection experiment is an ongoing long-term artificial selection experiment that has been conducted on the kernel of maize (Zea mays) in Illinois since 1896, making it the longest-running directional selection project conducted on plants and one of the longest-running experiments in all of biology.
The Novak–Tyson model, first published in the paper titled "Numerical analysis of a comprehensive model of M-phase control in Xenopus oocyte extracts and intact embryos", builds on the Goldbeter and Tyson 1991 models in order to generate a unifying theory, encapsulating the observed dynamics of the cyclin-MPF relationship. [1]
Stephen Joseph Elledge Born (1956-08-07) August 7, 1956 (age 68) Paris, Illinois Nationality American Education University of Illinois Urbana-Champaign (BSc) Massachusetts Institute of Technology (PhD) Known for Cell cycle research DNA repair research Spouse Mitzi Kuroda Awards NAS Award in Molecular Biology Breakthrough Prize in Life Sciences Genetics Society of America Medal Dickson Prize ...
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A top Costco executive sounded the alarm on the potential consequences of President-elect Donald Trump’s proposed tariffs — warning that it will raise prices of goods across the board. “When ...
An alpha-helix with hydrogen bonds (yellow dots) The α-helix is the most abundant type of secondary structure in proteins. The α-helix has 3.6 amino acids per turn with an H-bond formed between every fourth residue; the average length is 10 amino acids (3 turns) or 10 Å but varies from 5 to 40 (1.5 to 11 turns).
This problem can only be diagnosed if all the other problems that cause similar symptoms are ruled out (1), so just limping and walking on the top of the feet could be caused by something else on ...