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  2. Regulation of gene expression - Wikipedia

    en.wikipedia.org/wiki/Regulation_of_gene_expression

    Regulation of gene expression, or gene regulation, [1] includes a wide range of mechanisms that are used by cells to increase or decrease the production of specific gene products (protein or RNA). Sophisticated programs of gene expression are widely observed in biology, for example to trigger developmental pathways, respond to environmental ...

  3. Transcriptional regulation - Wikipedia

    en.wikipedia.org/wiki/Transcriptional_regulation

    Enhancers control cell-type-specific gene expression programs, most often by looping through long distances to come in physical proximity with the promoters of their target genes. [39] In a study of brain cortical neurons, 24,937 loops were found, bringing enhancers to promoters. [ 36 ]

  4. Transcription factor - Wikipedia

    en.wikipedia.org/wiki/Transcription_factor

    Transcription factors are essential for the regulation of gene expression and are, as a consequence, found in all living organisms. The number of transcription factors found within an organism increases with genome size, and larger genomes tend to have more transcription factors per gene.

  5. Regulatory sequence - Wikipedia

    en.wikipedia.org/wiki/Regulatory_sequence

    A regulatory sequence is a segment of a nucleic acid molecule which is capable of increasing or decreasing the expression of specific genes within an organism. Regulation of gene expression is an essential feature of all living organisms and viruses.

  6. Gene expression - Wikipedia

    en.wikipedia.org/wiki/Gene_expression

    Regulation of gene expression is the control of the amount and timing of appearance of the functional product of a gene. Control of expression is vital to allow a cell to produce the gene products it needs when it needs them; in turn, this gives cells the flexibility to adapt to a variable environment, external signals, damage to the cell, and ...

  7. Regulator gene - Wikipedia

    en.wikipedia.org/wiki/Regulator_gene

    Gene regulatory pathway. In genetics, a regulator gene, regulator, or regulatory gene is a gene involved in controlling the expression of one or more other genes. Regulatory sequences, which encode regulatory genes, are often at the five prime end (5') to the start site of transcription of the gene they regulate. In addition, these sequences ...

  8. Eukaryotic transcription - Wikipedia

    en.wikipedia.org/wiki/Eukaryotic_transcription

    The regulation of gene expression in eukaryotes is achieved through the interaction of several levels of control that acts both locally to turn on or off individual genes in response to a specific cellular need and globally to maintain a chromatin-wide gene expression pattern that shapes cell identity.

  9. Gene silencing - Wikipedia

    en.wikipedia.org/wiki/Gene_silencing

    Gene silencing is the regulation of gene expression in a cell to prevent the expression of a certain gene. [ 1 ] [ 2 ] Gene silencing can occur during either transcription or translation and is often used in research.