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  2. Bone resorption - Wikipedia

    en.wikipedia.org/wiki/Bone_resorption

    Physiological bone resorption is an integral part of bone functioning, while the bone is constantly growing thanks to two processes — breakdown and formation of bone tissue. [23] Locally, it could be manifested in tooth eruption when the movement of a tooth follicle is followed by an active resorption of jaw bone tissue.

  3. Bone remodeling - Wikipedia

    en.wikipedia.org/wiki/Bone_remodeling

    Bone tissue is removed by osteoclasts, and then new bone tissue is formed by osteoblasts. Both processes utilize cytokine (TGF-β, IGF) signalling.In osteology, bone remodeling or bone metabolism is a lifelong process where mature bone tissue is removed from the skeleton (a process called bone resorption) and new bone tissue is formed (a process called ossification or new bone formation).

  4. Bone remodeling period - Wikipedia

    en.wikipedia.org/wiki/Bone_remodeling_period

    In other words, what this formula means is that the bone remodeling period is equivalent to the thickness of the microscopic segment of bone being formed divided by the rate at which it forms. If the mean linear rate of bone resorption is known, the bone resorption portion (σ r) can be similarly calculated: [5]

  5. Osteolysis - Wikipedia

    en.wikipedia.org/wiki/Osteolysis

    Osteolysis is an active resorption of bone matrix by osteoclasts and can be interpreted as the reverse of ossification.Although osteoclasts are active during the natural formation of healthy bone the term "osteolysis" specifically refers to a pathological process.

  6. Resorption - Wikipedia

    en.wikipedia.org/wiki/Resorption

    Resorption is the absorption of cells or tissue into the circulatory system, usually by osteoclasts. [1] Types of resorption include: Bone resorption; Herniated Disc Resorption; Tooth resorption [2] Fetal resorption; Blood resorption

  7. Bone - Wikipedia

    en.wikipedia.org/wiki/Bone

    Bone is constantly being created and replaced in a process known as remodeling. This ongoing turnover of bone is a process of resorption followed by replacement of bone with little change in shape. This is accomplished through osteoblasts and osteoclasts. Cells are stimulated by a variety of signals, and together referred to as a remodeling unit.

  8. RANKL - Wikipedia

    en.wikipedia.org/wiki/RANKL

    RANKL, through its ability to stimulate osteoclast formation and activity, is a critical mediator of bone resorption and overall bone density. Overproduction of RANKL is implicated in a variety of degenerative bone diseases, such as rheumatoid arthritis and psoriatic arthritis. In addition to degenerative bone diseases, bone metastases can also ...

  9. Medication-related osteonecrosis of the jaw - Wikipedia

    en.wikipedia.org/wiki/Medication-related_osteo...

    Particular medications can result in MRONJ, a serious but uncommon side effect in certain individuals. Such medications are frequently used to treat diseases that cause bone resorption such as osteoporosis, or to treat cancer. The main groups of drugs involved are anti-resorptive drugs, and anti-angiogenic drugs.