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The protein encoded by this gene is a homeodomain protein that lacks certain conserved residues required for DNA binding. It was reported that choriocarcinoma cell lines and tissues failed to express this gene, which suggested the possible involvement of this gene in malignant conversion of placental trophoblasts.
The same Hox protein can act as a repressor at one gene and an activator at another. The ability of Hox proteins to bind DNA is conferred by a part of the protein referred to as the homeodomain. The homeodomain is a 60-amino-acid-long DNA-binding domain (encoded by its corresponding 180-base-pair DNA sequence, the homeobox
Homeobox genes encode homeodomain protein products that are transcription factors sharing a characteristic protein fold structure that binds DNA to regulate expression of target genes. [ 3 ] [ 4 ] [ 2 ] Homeodomain proteins regulate gene expression and cell differentiation during early embryonic development, thus mutations in homeobox genes can ...
Moody reveals the 10 worst eating habits that could be hindering your progress and keeping that belly fat intact. By addressing these habits head-on, you can pave the way for a slimmer, healthier you.
Meanwhile, about a quarter of non-overweight people are what epidemiologists call “the lean unhealthy.” A 2016 study that followed participants for an average of 19 years found that unfit skinny people were twice as likely to get diabetes as fit fat people. Habits, no matter your size, are what really matter.
8 Healthy Habits to Start Building 1. Eating a Balanced, Nutritious Diet. Perhaps unsurprisingly, healthy eating habits are instrumental, and those who eat healthier ingredients and quantities are ...
HOXB6 gene is only expressed in erythroid progenitor cells, which are the precursor to red blood cells used for transport of oxygen and carbon dioxide throughout the body. During development, the formation of the HOX gene factor happens in the first stages of fetal development , namely soon after the establishment of the mesoderm , which is the ...
Among Kentucky’s taxpayer-funded rehabilitation options is a network of 15 facilities — eight for men and seven for women — created about a decade ago and known as Recovery Kentucky. It represents the state’s central drug treatment effort, admitting thousands of addicts per year.