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The risk of transmission from anal intercourse is especially high, estimated as 1.4–1.7% per act in both heterosexual and homosexual contacts. [60] [61] While the risk of transmission from oral sex is relatively low, it is still present. [62]
When people are exposed to HIV-positive infectious bodily fluids either through skin puncture, contact with mucous membranes or contact with damaged skin, they are at risk for acquiring HIV. Pooled estimates give a risk of transmission with puncture exposures of 0.3% [115] and mucous membrane exposures 0.63%. [116]
The campaign seeks to spread the scientific evidence that undetectable means untransmittable. Since the beginning of the epidemic, perceptions and management of HIV infection have gone through many stages; from assuming the infectiousness, then discovering the routes of transmission (blood, sexual fluids, and breastfeeding), to prevention methods (education, condoms, PrEP, and PEP) and various ...
HIV-1 is more virulent and more infective than HIV-2, [20] and is the cause of the majority of HIV infections globally. The lower infectivity of HIV-2, compared to HIV-1, implies that fewer of those exposed to HIV-2 will be infected per exposure. Due to its relatively poor capacity for transmission, HIV-2 is largely confined to West Africa. [21]
The testing and treatment of HIV-positive mothers during pregnancy, childbirth, and breastfeeding has since led to the reduction of the risk of transmission by up to 95%. [15] A program for offering ARVs for life to any HIV-positive pregnant woman called "Option B+" served as a precursor to the "test and treat" strategy that is now being rolled ...
This contrasts with seroconcordant relationships, in which both partners are of the same HIV status. Without effective prevention measures, serodiscordant relationships can significantly contribute to the spread of HIV/AIDS, with the risk varying based on the type and frequency of sexual activity and the viral load of the HIV-positive partner. [2]
The risk of HIV transmission from mother to child is most directly related to the plasma viral load of the mother. Untreated mothers with a high (HIV RNA greater than 100,000 copies/mL) have a transmission risk of over 50%. [25] For women with a lower viral load (HIV RNA less than 1000 copies/mL), the risk of transmission is less than 1%. [26]
HIV-infected women remain fertile, although in late stages of HIV disease a pregnant woman may have a higher risk of miscarriage. Normally, the risk of transmitting HIV to the unborn child is between 15 and 30%. However, this may be reduced to just 2–3% if patients carefully follow medical guidelines. [35] [36]
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