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  2. Fibroblast growth factor and mesoderm formation - Wikipedia

    en.wikipedia.org/wiki/Fibroblast_growth_factor...

    This article is about the role of fibroblast growth factor signaling in mesoderm formation. Mesoderm formation is a complex developmental process involving an intricate network of signaling pathways that coordinate their activities to ensure that a selective group of cells will eventually give rise to mesodermal tissues in the adult organism.

  3. Fibroblast - Wikipedia

    en.wikipedia.org/wiki/Fibroblast

    A fibroblast is a type of biological cell typically with a spindle shape [1] ... a feature used as a marker to distinguish their mesodermal origin. [6] However, this ...

  4. List of human cell types derived from the germ layers

    en.wikipedia.org/wiki/List_of_human_cell_types...

    This page was last edited on 12 December 2024, at 14:30 (UTC).; Text is available under the Creative Commons Attribution-ShareAlike 4.0 License; additional terms may apply.

  5. Lateral plate mesoderm - Wikipedia

    en.wikipedia.org/wiki/Lateral_plate_mesoderm

    The lateral plate mesodermal cells secrete a fibroblast growth factor (FGF7 and FGF10, presumably) to induce the overlying ectoderm to form an important organizing structure called the apical ectodermal ridge (AER). The AER reciprocatively secretes FGF8 and FGF4 which maintains the FGF10 signal and induces proliferation in the mesoderm. [3]

  6. Limb development - Wikipedia

    en.wikipedia.org/wiki/Limb_development

    The lateral plate mesodermal cells secrete fibroblast growth factors (FGF7 and FGF10) to induce the overlying ectoderm to form an organizer at the end of the limb bud, called the apical ectodermal ridge (AER), which guides further development and controls cell death. [8]

  7. Fibroblast growth factor - Wikipedia

    en.wikipedia.org/wiki/Fibroblast_growth_factor

    Fibroblast growth factors (FGF) are a family of cell signalling proteins produced by macrophages; they are involved in a wide variety of processes, most notably as crucial elements for normal development in animal cells. Any irregularities in their function lead to a range of developmental defects.

  8. Germ layer - Wikipedia

    en.wikipedia.org/wiki/Germ_layer

    A germ layer is a primary layer of cells that forms during embryonic development. [1] The three germ layers in vertebrates are particularly pronounced; however, all eumetazoans (animals that are sister taxa to the sponges) produce two or three primary germ layers.

  9. Paraxial mesoderm - Wikipedia

    en.wikipedia.org/wiki/Paraxial_mesoderm

    Members of the fibroblast growth factor family also play an important role, as does the Wnt pathway. In particular, Noggin, a downstream target of the Wnt pathway, antagonizes BMP signaling, forming boundaries where antagonists meet and limiting this signaling to a particular region of the mesoderm.