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A prolactinoma is a tumor of the pituitary gland that produces the hormone prolactin.It is the most common type of functioning pituitary tumor. [1] Symptoms of prolactinoma are due to abnormally high levels of prolactin in the blood (hyperprolactinemia), or due to pressure of the tumor on surrounding brain tissue and/or the optic nerves.
Hyperpituitarism is a condition due to the primary hypersecretion of pituitary hormones; [3] [medical citation needed] it typically results from a pituitary adenoma.In children with hyperpituitarism, disruption of growth regulation is rare, either because of hormone hypersecretion or because of manifestations caused by local compression of the adenoma.
Individuals with hyperprolactinemia may present with symptoms including galactorrhea, hypogonadism effects, and/or infertility. The magnitude that prolactin is elevated can be used as an indicator of the etiology of the hyperprolactinemia diagnosis. Prolactin levels over 250 ng/mL may suggest prolactinoma.
Also, a pituitary adenoma can cause symptoms of increased intracranial pressure. Prolactinomas often start to give symptoms especially during pregnancy, when the increased hormone level estrogen can increase the tumor's growth rate. [10] Various types of headaches are common in patients with pituitary adenomas.
5617 19109 Ensembl ENSG00000172179 ENSMUSG00000021342 UniProt P01236 P06879 RefSeq (mRNA) NM_000948 NM_001163558 NM_001163530 NM_011164 RefSeq (protein) NP_000939 NP_001157030 NP_001157002 NP_035294 Location (UCSC) Chr 6: 22.29 – 22.3 Mb Chr 13: 27.24 – 27.25 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Prolactin (PRL), also known as lactotropin and mammotropin, is a protein ...
Few periods of life are more closely monitored and supervised than during one's pregnancy. Throughout this time, trained medical professionals conduct a series of prenatal visits with the mother ...
(Reuters) -Major food companies, including Kraft Heinz, Mondelez and Coca-Cola, were hit with a new lawsuit in the U.S. on Tuesday accusing them of designing and marketing "ultra-processed" foods ...
This pituitary tumor, prolactinoma, results in an overproduction of prolactin, or hyperprolactinemia. [2] This type of cause is classified under organic hyperprolactinemia. [ 16 ] In pregnancy, the lactrotroph production increases through means of cellular proliferation of which gives rise to potential for neoplastic development. [ 2 ]
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