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Intravenous (IV) iron infusion is a therapy in which a combination of iron and saline solution is delivered directly into the bloodstream through a vein, in patients suffering iron deficiency, iron-deficiency anaemia and chronic kidney disease.
Iron preparation is the formulation for iron supplements indicated in prophylaxis and treatment of iron-deficiency anemia. Examples of iron preparation include ferrous sulfate, ferrous gluconate, and ferrous fumarate. It can be administered orally, and by intravenous injection, or intramuscular injection. [1] Early Iron Supplement for Anemia
Iron sucrose has also been shown to significantly lower the risk of gastrointestinal problems when compared to oral iron treatments. It has a much lower rate of serious allergic reactions in comparison to other iron substitution treatments (around 0.002% in iron sucrose in comparison to 0.04-2.3% in other treatments).
Sodium ferric gluconate complex, sold under the brand name Ferrlecit, is an intravenously administered iron medication for the treatment of iron deficiency anemia in adults and in children aged six years and older with chronic kidney disease receiving hemodialysis who are receiving supplemental epoetin therapy. [2]
Thiolate-ligated oxoiron(IV) is formed by the oxidation of a precursor, [Fe II (TMCS)](PF 6) (TMCS = 1-mercaptoethyl-4,8,11-trimethyl-1,4,8,11-tetraza cyclotetradecane), and 3-5 equivalents of H 2 O 2 at -60 ˚C in methanol. The iron(IV) compound is deep blue in color and shows intense absorption features at 460 nm, 570 nm, 850 nm, and 1050 nm.
Low-pressure phase diagram of pure iron. BCC is body centered cubic and FCC is face-centered cubic. Iron-carbon eutectic phase diagram, showing various forms of Fe x C y substances. Iron allotropes, showing the differences in structure. The alpha iron (α-Fe) is a body-centered cubic (BCC) and the gamma iron (γ-Fe) is a face-centered cubic (FCC).
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An equianalgesic chart is a conversion chart that lists equivalent doses of analgesics (drugs used to relieve pain). Equianalgesic charts are used for calculation of an equivalent dose (a dose which would offer an equal amount of analgesia) between different analgesics. [1]