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Neuromyelitis optica spectrum disorders (NMOSD) are a spectrum of autoimmune diseases characterized by acute inflammation of the optic nerve (optic neuritis, ON) and the spinal cord . [1] [2] [3] Episodes of ON and myelitis can be simultaneous or successive. A relapsing disease course is common, especially in untreated patients. [1] [4]
Steps to achieve the same depend on mechanism of the hypertropia and identification of the offending muscles causing the misalignment. Various surgical procedures have been described and should be offered after careful examination of eyes, including a detailed orthoptic examination focussing on the disturbances in ocular motility and visual status.
The optic nerve can be damaged when exposed to direct or indirect injury. Direct optic nerve injuries are caused by trauma to the head or orbit that crosses normal tissue planes and disrupts the anatomy and function of the optic nerve; e.g., a bullet or forceps that physically injures the optic nerve.
Another condition that produces similar symptoms is a cranial nerve disease. [3] Treatment depends on the type of strabismus and the underlying cause. [3] This may include the use of glasses and possibly surgery. [3] Some types benefit from early surgery. [3] Strabismus occurs in about 2% of children. [3]
The morning glory disc anomaly (MGDA) is a congenital deformity resulting from failure of the optic nerve to completely form in utero. [1] The term was coined in 1970 by Kindler, noting a resemblance of the malformed optic nerve to the morning glory flower. [2] The condition is usually unilateral. [3]
The exact mechanism of optic nerve ischemia in these cases remains unclear, but contributing factors may include hypotension, anemia, hypoxia, and changes in the autoregulation of optic nerve arterial blood flow. The incidence of ischemic optic neuropathy leading to vision loss following general surgeries ranges between 0.1% and 0.002%.
Non-arteritic anterior ischemic optic neuropathy, or NAION, is a condition that affects the optic nerve, a bundle of fibers that connects to the back of the eye and carries signals to the brain so ...
The RGCs axons form the optic nerve. Therefore, the disease can be considered of the central nervous system. [ 2 ] Dominant optic atrophy was first described clinically by Batten in 1896 and named Kjer’s optic neuropathy in 1959 after Danish ophthalmologist Poul Kjer , who studied 19 families with the disease. [ 3 ]