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The disorder can cause heart abnormalities and seizures if the amount of methemoglobin in the blood exceeds 20 percent, but at levels between 10 and 20 percent it can cause blue skin without other symptoms. Most of the Fugates lived long and healthy lives. The "bluest" of the blue Fugates, Luna Stacy, had 13 children and lived to age 84. [6]
Martin Fugate and Elizabeth Smith, who had married and settled near Hazard, Kentucky, around 1800, were both carriers of the recessive methemoglobinemia (met-H) gene, as was a nearby clan with whom the Fugates descendants intermarried. As a result, many descendants of the Fugates were born with met-H. [31] [32] [33] [34]
The most dramatic symptom of argyria is that the skin turns blue or blue-gray. It may take the form of generalized argyria or local argyria. Generalized argyria affects large areas over much of the visible surface of the body. Local argyria shows in limited regions of the body, such as patches of skin, parts of the mucous membrane or the ...
Plaque build-up often doesn’t cause symptoms, but it can block blood flow to vital organs like your heart. Coronary artery disease occurs when atherosclerosis affects the arteries supplying ...
HEART DISEASE IS the No. 1 cause of death for men (and women) in the U.S.—but not everyone knows that. Almost half of adults have some kind of cardiovascular disease, including coronary heart ...
Stage A Defined as: At high risk for heart failure but without structural heart disease (defects in the heart from aging, injury, infection, or heart defect at birth), or symptoms of heart failure.
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