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  2. Lymphocyte - Wikipedia

    en.wikipedia.org/wiki/Lymphocyte

    A lymphocyte is a type of white blood cell (leukocyte) in the immune system of most vertebrates. [1] Lymphocytes include T cells (for cell-mediated and cytotoxic adaptive immunity), B cells (for humoral, antibody-driven adaptive immunity), [2] [3] and innate lymphoid cells (ILCs; "innate T cell-like" cells involved in mucosal immunity and homeostasis), of which natural killer cells are an ...

  3. B cell - Wikipedia

    en.wikipedia.org/wiki/B_cell

    Of the three B cell subsets, FO B cells preferentially undergo T cell-dependent activation while MZ B cells and B1 B cells preferentially undergo T cell-independent activation. [ 16 ] B cell activation is enhanced through the activity of CD21 , a surface receptor in complex with surface proteins CD19 and CD81 (all three are collectively known ...

  4. Plasma cell - Wikipedia

    en.wikipedia.org/wiki/Plasma_cell

    The T cell-dependent processes are subdivided into primary and secondary responses: a primary response (meaning that the T cell is present at the time of initial contact by the B cell with the antigen) produces short-lived cells that remain in the extramedullary regions of lymph nodes; a secondary response produces longer-lived cells that ...

  5. Lymph node - Wikipedia

    en.wikipedia.org/wiki/Lymph_node

    They present the antigen to T cells and, if there is a T cell with the appropriate T cell receptor, it will be activated. [25] B cells acquire antigen directly from the afferent lymph. If a B cell binds its cognate antigen it will be activated. Some B cells will immediately develop into antibody secreting plasma cells, and secrete IgM.

  6. List of immune cells - Wikipedia

    en.wikipedia.org/wiki/List_of_immune_cells

    Plasma cell: Lymphocyte: B cell: Plasma B cells; Effector B cells; Plasmocytus; 8-10 Active B cells that produces large amounts of antibodies [4] [15] Memory B cell: Lymphocyte: B cell: MBC; 8-10 Memorizes the characteristics of the antigens; Triggers an accelerated and robust secondary immune response [4] [16] Killer T cell: Lymphocyte: T cell ...

  7. Lymph node stromal cell - Wikipedia

    en.wikipedia.org/wiki/Lymph_node_stromal_cell

    In the nodules, T lymphocytes are located in the T cell zone. B lymphocytes are located in the B cell follicle. The primary B cell follicle matures in germinal centers. In the medulla are hematopoietic cells (which contribute to the formation of the blood) and stromal cells. Near the medulla is the hilum of lymph node.

  8. Adaptive immune system - Wikipedia

    en.wikipedia.org/wiki/Adaptive_immune_system

    In all vertebrates except Agnatha, B cells and T cells are produced by stem cells in the bone marrow. [6] T cell progenitors then migrate from the bone marrow to the thymus, where they develop further. In an adult animal, the peripheral lymphoid organs contain a mixture of B and T cells in at least three stages of differentiation: [citation needed]

  9. T helper cell - Wikipedia

    en.wikipedia.org/wiki/T_helper_cell

    In 1991, three groups reported discovering CD154, which is the molecular basis of T cell helper function. Seth Lederman at Columbia University generated a murine monoclonal antibody, 5c8 that inhibited contact-dependent T cell helper function in human cells which characterized the 32 kDa surface protein transiently expressed on CD4 + T cells. [16]