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Example organisms used for high-content screening include the fruit fly (Drosophila melanogaster), zebrafish (Danio rerio) and mice (Mus musculus). [13] In some instances the term phenotypic screening is used to include the serendipitous findings that occur in clinical trial settings particularly when new and unanticipated therapeutic effects ...
Genetic screens can provide important information on gene function as well as the molecular events that underlie a biological process or pathway. While genome projects have identified an extensive inventory of genes in many different organisms, genetic screens can provide valuable insight as to how those genes function.
The psychologist Steven Pinker states that "group selection has no useful role to play in psychology or social science", since in these domains it "is not a precise implementation of the theory of natural selection, as it is, say, in genetic algorithms or artificial life simulations. Instead [in psychology] it is a loose metaphor, more like the ...
Frequency-dependent selection is an evolutionary process by which the fitness of a phenotype or genotype depends on the phenotype or genotype composition of a given population. In positive frequency-dependent selection, the fitness of a phenotype or genotype increases as it becomes more common.
Evolutionary psychologists consider Charles Darwin's theory of natural selection to be important to an understanding of psychology. [1] Natural selection occurs because individual organisms who are genetically better suited to the current environment leave more descendants, and their genes spread through the population, thus explaining why organisms fit their environments so closely. [1]
Fisher's principle is rooted in the concept of frequency-dependent selection, though Fisher's principle is not frequency-dependent selection per se. Frequency-dependent selection, in this scenario, is the logic that the probability of an individual being able to breed is dependent on the frequency of the opposite sex in relation to its own sex.
Both selection and screening can be performed in living cells (in vivo evolution) or performed directly on the protein or RNA without any cells (in vitro evolution). [ 21 ] [ 22 ] During in vivo evolution, each cell (usually bacteria or yeast ) is transformed with a plasmid containing a different member of the variant library.
Cognitive biology is an emerging science that regards natural cognition as a biological function. [1] It is based on the theoretical assumption that every organism—whether a single cell or multicellular—is continually engaged in systematic acts of cognition coupled with intentional behaviors, i.e., a sensory-motor coupling. [2]