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  2. Direct factor Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Direct_factor_Xa_inhibitors

    Antistasin, the first discovered naturally occurring direct Xa inhibitor Rivaroxaban, the first synthetic direct Xa inhibitor marketed as a drug Prior to the introduction of direct factor Xa inhibitors, vitamin K antagonists such as warfarin were the only oral anticoagulants for over 60 years, and together with heparin have been the main blood ...

  3. Rivaroxaban - Wikipedia

    en.wikipedia.org/wiki/Rivaroxaban

    Rivaroxaban, sold under the brand name Xarelto among others, is an anticoagulant medication (blood thinner) used to treat and prevent blood clots. [8] Specifically it is used to treat deep vein thrombosis and pulmonary emboli and prevent blood clots in atrial fibrillation and following hip or knee surgery. [ 8 ]

  4. Discovery and development of direct Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    Rivaroxaban. During the SAR development of rivaroxaban, researchers realized that adding a 5-chlorothiophene-2-carboxamide group to the oxazolidonine core could increase the potency by 200 fold, which had previously been too weak for medical use. In addition to this discovery, a clear preference for the (S)-configuration was confirmed.

  5. Alcohol is not good for us. 5 tips to stay safe(r) if you drink

    www.aol.com/drink-not-drink-5-tips-142139741.html

    Study participants who were given alcoholic drinks received a specific amount of alcohol, based on sex and weight, that would get them to a 0.06% blood alcohol level, Kilmer said.

  6. The Worst Foods to Eat When Taking Wegovy for Weight Loss - AOL

    www.aol.com/worst-foods-eat-taking-wegovy...

    Keep a food log to track your food choices and see if they correlate with any symptoms. Make healthier swaps while preparing meals. For example, instead of using butter when cooking, opt for olive ...

  7. Vitamin K antagonist - Wikipedia

    en.wikipedia.org/wiki/Vitamin_K_antagonist

    We undertook a post-hoc analysis of data from the ROCKET AF (Rivaroxaban Once-Daily, Oral, Direct Factor Xa Inhibition Compared With Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation, n = 14,624) for stroke or non-CNS embolism within 30 days after temporary interruptions of 3 days or more, early permanent ...

  8. Semaglutide Weight Loss Drug Nausea: 8 Tips for Relieving It

    www.aol.com/semaglutide-weight-loss-drug-nausea...

    3. Avoid High-Fat Foods and Other Triggers. High-fat foods can make your nausea worse. Try avoiding: Fatty meats. Baked goods. Greasy or fried foods

  9. Anticoagulant - Wikipedia

    en.wikipedia.org/wiki/Anticoagulant

    An anticoagulant, commonly known as a blood thinner, is a chemical substance that prevents or reduces the coagulation of blood, prolonging the clotting time. [1] Some occur naturally in blood-eating animals, such as leeches and mosquitoes, which help keep the bite area unclotted long enough for the animal to obtain blood.