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  2. Sirtuin 4 - Wikipedia

    en.wikipedia.org/wiki/Sirtuin_4

    SIRT4 is a mitochondrial ADP-ribosyltransferase that inhibits mitochondrial glutamate dehydrogenase 1 activity, thereby downregulating insulin secretion in response to amino acids. [7] A deacetylation of malonyl-CoA decarboxylase enzyme by SIRT4 represses the enzyme activity, inhibiting fatty acid oxidation in muscle and liver cells.

  3. Serum free light-chain measurement - Wikipedia

    en.wikipedia.org/wiki/Serum_free_light-chain...

    Each immunoglobulin light-chain molecule contains approximately 220 amino acids in a single polypeptide chain that is folded to form constant and variable region domains. Each domain comprises two β-pleated sheets. The sheets are linked by a disulfide bridge and together form a roughly barrel-shaped structure known as a β-barrel. The variable ...

  4. Xanthoproteic reaction - Wikipedia

    en.wikipedia.org/wiki/Xanthoproteic_reaction

    If the test is positive the proof is neutralized with an alkali, turning dark yellow. The yellow colour is due to xanthoproteic acid which is formed due to nitration of certain amino acids, most common examples being tyrosine and tryptophan. [1] This chemical reaction is a qualitative test, determining the presence or absence of proteins.

  5. Acute-phase protein - Wikipedia

    en.wikipedia.org/wiki/Acute-phase_protein

    Positive acute-phase proteins serve (as part of the innate immune system) different physiological functions within the immune system.Some act to destroy or inhibit growth of microbes, e.g., C-reactive protein, mannose-binding protein, [3] complement factors, ferritin, ceruloplasmin, serum amyloid A and haptoglobin.

  6. Kell antigen system - Wikipedia

    en.wikipedia.org/wiki/Kell_antigen_system

    The antibodies lead to destruction of the red blood cells with resulting anemia. Similarly, a pregnant woman may develop antibodies against fetal red blood cells, resulting in destruction, anemia, and hydrops fetalis in a process known as hemolytic disease of the newborn (HDN). Both AIHA and HDN may be severe when caused by anti-Kell antibodies ...

  7. p16 - Wikipedia

    en.wikipedia.org/wiki/P16

    p16 was discovered in 1993. It is a protein with 148 amino acids and a molecular weight of 16 kDa that comprises four ankyrin repeats. [8] The name of p16 is derived from its molecular weight, and the alternative name p16 INK4a refers to its role in inhibiting cyclin-dependent kinase CDK4. [8]

  8. Couple Charged with Child Abuse After Botched Home ...

    www.aol.com/couple-charged-child-abuse-botched...

    A Missouri couple has been charged with child abuse after police claim they performed a circumcision on a child at their home despite not having the medical training to do so.

  9. Alanine transaminase - Wikipedia

    en.wikipedia.org/wiki/Alanine_transaminase

    Alanine transaminase (ALT), also known as alanine aminotransferase (ALT or ALAT), formerly serum glutamate-pyruvate transaminase (GPT) or serum glutamic-pyruvic transaminase (SGPT), is a transaminase enzyme (EC 2.6.1.2) that was first characterized in the mid-1950s by Arthur Karmen and colleagues. [1]

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