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Pleurodesis is a medical procedure in which part of the pleural space is artificially obliterated. [1] It involves the adhesion of the visceral and the costal pleura. The mediastinal pleura is spared.
Pleurodesis is the obliteration of the pleural space, achieved by adhering the visceral pleura on the lung surface to the costal pleura of the chest wall. Adhesion is caused by inflammation and subsequent scarring of the pleural layers. Inflammation may be induced by either physical or chemical irritation.
If a chest tube is already in place, various agents may be instilled through the tube to achieve chemical pleurodesis, such as talc, tetracycline, minocycline or doxycycline. Results of chemical pleurodesis tend to be worse than when using surgical approaches, [ 12 ] [ 15 ] but talc pleurodesis has been found to have few negative long-term ...
Pulmonary talcosis is a pulmonary disorder caused by talc. It has been related to silicosis resulting from inhalation of talc and silicates. It is also tied to heroin use where talc might be used as an adulterant to increase weight and street value. [1] It is one of several noted associations and possible risks of street heroin use. [2]
For this reason, more permanent treatments are usually used to prevent fluid recurrence. Standard treatment involves inserting an indwelling pleural catheter and pleurodesis. [16] However, this treatment requires an inpatient stay of approximately 2–7 days, can be painful and has a significant failure rate.
This fluid can lead to complications such as hypoxia due to lung collapse from the fluid, or fibrothorax if scarring occurs. Repeated effusions may require chemical ( talc , bleomycin , tetracycline / doxycycline ), or surgical pleurodesis , in which the two pleural surfaces are scarred to each other so that no fluid can accumulate between them.
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Complication of surgery, trauma, cancer, ... talc pleurodesis is recommended; ... Chemical pleurodesis is an option, since the leaking of lymphatic fluids is stopped ...