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In 1981, a paper by Gosselin estimated that the lethal dose is between 50 and 500 mg/kg. Doses as high as 15–20 mg/kg are taken by some recreational users. A single case study suggests that the antidote to dextromethorphan overdose is naloxone, administered intravenously. [17]
Dextromethorphan, sold under the brand name Robitussin among others, is a cough suppressant used in many cough and cold medicines. [6] In 2022, the US Food and Drug Administration (FDA) approved the combination dextromethorphan/bupropion to serve as a rapid-acting antidepressant in people with major depressive disorder .
Early 20th century "Frog In Your Throat" box, containing lozenges made of cubeb, tolu balsam, liquorice, white horehound and wild cherry extracts.. Candies to soothe the throat date back to 1000 BC in Egypt's Twentieth Dynasty, when they were made from honey flavored with citrus, herbs, and spices.
However, in children, it has not been found to be effective. [12] Codeine was once viewed as the "gold standard" in cough suppressants, but this position is now questioned. [13] Some placebo-controlled trials have found that it is ineffective against some forms of cough, including acute cough in children. [14] [15] It is thus not recommended ...
Robitussin Honey CF Max NT Adult 8oz Lots: T08740 (June 30, 2026), T08742 (June 30, 2026) The elderly and very young people are most likely to experience complications from fungemia.
Effective dose: It is the minimum dose or concentration of a drug that produces a biological response in 50% of a population being studied. Median lethal dose: For either drugs or toxins, it is a toxic unit that measures the minimum dose that causes death (lethal dose) in 50% of cases.
The most serious charge against the man accused of killing the UnitedHealthcare CEO in broad daylight last week on a Manhattan sidewalk is murder in the second degree. Given the image of the ...
The Broselow Tape relates a child's height as measured by the tape to their weight to provide medical instructions including medication dosages, the size of the equipment that should be used, and the level of energy when using a defibrillator. Particular to children is the need to calculate all these therapies for each child individually.
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