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Fluoxetine, sold under the brand name Prozac, among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. [2] It is used for the treatment of major depressive disorder , obsessive–compulsive disorder (OCD), anxiety , bulimia nervosa , panic disorder , and premenstrual dysphoric disorder . [ 2 ]
They showed that "In terms of efficacy, all antidepressants were more effective than placebo, with odds ratios (ORs) ranging between 2.13 (95% credible interval [CrI] 1.89–2.41) for amitriptyline and 1.37 (1.16–1.63) for reboxetine." [16] The odds ratios were specifically in terms of response rates (≥50% reduction in observer-rated ...
For adolescents, cognitive behavioral therapy and interpersonal therapy have been empirically supported as effective treatment options. [1] [20] For children and adolescents with moderate-to-severe depressive disorder, fluoxetine seems to be best treatment (either with or without cognitive behavioural therapy) but more research is needed to be ...
The most commonly used classes of medications for these disorders are antidepressants, antipsychotics, and lithium. Unfortunately, these medications are associated with significant neurotoxicities. Psychiatric medications carry risk for neurotoxic adverse effects .
To get antidepressants, you’ll first need a prescription. Primary care providers (PCPs), psychiatric nurse practitioners, and psychiatrists are all qualified to prescribe antidepressant medications.
Most antidepressants, including SNRIs, are safe and effective in the geriatric population. The geriatric population is at greater risk for adverse effects relating to drug interaction as they are more likely to experience polypharmacy. [98] Decisions are often based on co-morbid conditions, drug interactions, and patient tolerance.
Also, currently available antidepressants all elicit undesirable side-effects, and new agents should be divested of the distressing side-effects of both first and second-generation antidepressants. [6] Another serious drawback of all antidepressants is the requirement for long-term administration prior to maximal therapeutic efficacy.
The October 10 recall is due to the presence of N-nitroso-duloxetine, a chemical that is toxic if swallowed and is suspected of causing cancer, according to the National Library of Medicine.