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In genetics, a transcription terminator is a section of nucleic acid sequence that marks the end of a gene or operon in genomic DNA during transcription. This sequence mediates transcriptional termination by providing signals in the newly synthesized transcript RNA that trigger processes which release the transcript RNA from the transcriptional ...
Tus, also known as terminus utilization substance, is a protein that binds to terminator sequences and acts as a counter-helicase when it comes in contact with an advancing helicase. [2] The bound Tus protein effectively halts DNA polymerase movement. [2] Tus helps end DNA replication in prokaryotes. [2]
Intrinsic terminator containing an RNA hairpin rich in guanine and cytosine as well as a region high in uracil. The two types of termination signals in bacteria are intrinsic and factor-dependent terminators. [4] Intrinsic termination occurs when a specific sequence on the growing RNA strand elicits detachment of RNA polymerase from the RNA-DNA ...
Among these genes, however, are regulators whose products allow the next set of phage genes to be expressed. One of these types of regulator is an antitermination protein. In the absence of the antitermination protein, RNA polymerase terminates at the terminator. When the antitermination protein is present, it continues past the terminator. [1]
This bacteriophage protein 7 stops transcription termination by blocking the RNA polymerase (RNAP) RNA-exit channel and impeding RNA-hairpin formation at the intrinsic terminator. Furthermore, bacteriophage protein 7 inhibits RNAP-clamp motions. [8] Shortening the C-terminal half-helix of the RNAP slightly decreases the inhibitory activity.
In molecular biology, the ter site, also known as DNA replication terminus binding-site, refers to a protein domain which binds to the DNA replication terminus site.Ter-binding proteins are found in some bacterial species, and include the Tus protein which is part of the common Ter-Tus binding domain.
Arnold Schwarzenegger has been many things during the course of his career — bodybuilder, the Terminator and governor of California, to name a few. He may now be adding Santa Claus to his résumé.
A ρ factor (Rho factor) is a bacterial protein involved in the termination of transcription. [1] Rho factor binds to the transcription terminator pause site, an exposed region of single stranded RNA (a stretch of 72 nucleotides) after the open reading frame at C-rich/G-poor sequences that lack obvious secondary structure.