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The optic vesicles project toward the sides of the head, and the peripheral part of each expands to form a hollow bulb, while the proximal part remains narrow and constitutes the optic stalk. [1] [2] Closure of the choroidal fissure in the optic stalk occurs during the seventh week of development. The former optic stalk is then called the optic ...
Only the epidermis in the head is competent to respond to the signal from the optic vesicles. Both the optic vesicle and the head epidermis are required for eye development. The competence of the head epidermis to respond to the optic vesicle signals comes from the expression of Pax6 in the epidermis. Pax6 is necessary and sufficient for eye ...
These diverticula make their appearance before the closure of the anterior end of the neural tube; [1] [2] after the closure of the tube around the 4th week of development, they are known as the optic vesicles. Previous studies of optic vesicles suggest that the surrounding extraocular tissues – the surface ectoderm and extraocular mesenchyme ...
Invagination is the process of folding in cells. The lens placode invaginates to later develop the lens or lens pit. The development of the lens placode is typically seen between 44 and 50 hours; invagination occurs shortly after at around the 50–55-hour mark.
The cephalic end of the neural groove exhibits several dilatations, which, when the tube is closed, assume the form of three vesicles; these constitute the three primary cerebral vesicles and correspond respectively to the future fore-brain (prosencephalon), midbrain (mesencephalon), and hind-brain (rhombencephalon).
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The lens placode under the direction of the optic vesicle gives rise to the lens of the eye. The adenohypophyseal placode , which forms the anterior lobe of the pituitary gland . Other animals
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