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Leydig cells release a class of hormones called androgens (19-carbon steroids). [8] They secrete testosterone, androstenedione and dehydroepiandrosterone (DHEA), when stimulated by the luteinizing hormone (LH), which is released from the anterior pituitary in response to gonadotropin releasing hormone which in turn is released by the hypothalamus.
A low testosterone level (hypogonadism) in men may be treated with testosterone administration. Prostate cancer may be treated by removing the major source of testosterone: testicle removal (orchiectomy); or agents which block androgens from accessing their receptor: antiandrogens.
A testicle or testis (pl. testes) is the gonad in all male bilaterians, including humans, and is homologous to the ovary in females. Its primary functions are the production of sperm and the secretion of androgens, primarily testosterone. The release of testosterone is regulated by luteinizing hormone (LH) from the anterior pituitary gland.
The main male sex organs are the penis and the scrotum, which contains the testicles that produce semen and sperm, which, as part of sexual intercourse, fertilize an ovum in the female's body; the fertilized ovum develops into a fetus, which is later born as an infant.
The androgen receptor is most closely related to the progesterone receptor, and progestins in higher dosages can block the androgen receptor. [11] [12] The main function of the androgen receptor is as a DNA-binding transcription factor that regulates gene expression; [13] however, the androgen receptor has other functions as well. [14]
As a refresher, testosterone is the main male sex hormone that’s mainly produced in the testicles, ... which are parts of the brain that tell the testicles to produce testosterone, can lower ...
Testosterone, which is produced by your testicles, “plays a key role in the development of characteristics like libido, and growth of the penis and testicles,” says Jamin Brahmbhatt, MD, a ...
Testosterone is the primary male sex hormone and androgen in males. [3] In humans, testosterone plays a key role in the development of male reproductive tissues such as testicles and prostate, as well as promoting secondary sexual characteristics such as increased muscle and bone mass, and the growth of body hair.
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