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  2. Endochondral ossification - Wikipedia

    en.wikipedia.org/wiki/Endochondral_ossification

    On the other hand, endochondral ossification starts with mesenchymal tissue turning into an intermediate cartilage stage, which is eventually substituted by bone. [3] Endochondral ossification is responsible for development of most bones including long and short bones, [4] the bones of the axial (ribs and vertebrae) and the appendicular ...

  3. Ossification - Wikipedia

    en.wikipedia.org/wiki/Ossification

    Diagram showing stages of endochondral ossification. Endochondral ossification is the formation of long bones and other bones. This requires a hyaline cartilage precursor. There are two centers of ossification for endochondral ossification. The primary center. In long bones, bone tissue first appears in the diaphysis (middle of shaft).

  4. Development of joints - Wikipedia

    en.wikipedia.org/wiki/Development_of_joints

    The process of endochondral ossification, which converts the cartilage models into bone, begins by the twelfth week of embryonic development. At birth, ossification of much of the bone has occurred, but the hyaline cartilage of the epiphyseal plate will remain throughout childhood and adolescence to allow for bone lengthening.

  5. Ossification center - Wikipedia

    en.wikipedia.org/wiki/Ossification_center

    In long bones, the secondary centers appear in the epiphyses. [2] At the end of the formation of the secondary ossification center, the only two areas where the cartilage remains is at the articular cartilage covering the epiphysis and at the epiphyseal plate between the epiphysis and diaphysis. [3] A schematic for long bone endochondral ...

  6. Long bone - Wikipedia

    en.wikipedia.org/wiki/Long_bone

    The longitudinal growth of long bones is a result of endochondral ossification at the epiphyseal plate. Bone growth in length is stimulated by the production of growth hormone (GH), a secretion of the anterior lobe of the pituitary gland .

  7. Bone - Wikipedia

    en.wikipedia.org/wiki/Bone

    Endochondral ossification occurs in long bones and most other bones in the body; it involves the development of bone from cartilage. This process includes the development of a cartilage model, its growth and development, development of the primary and secondary ossification centers, and the formation of articular cartilage and the epiphyseal ...

  8. Chondrogenesis - Wikipedia

    en.wikipedia.org/wiki/Chondrogenesis

    A spotted gar larva at 22 days stained for cartilage (blue) and bone (red). Chondrogenesis is the biological process through which cartilage tissue is formed and developed. . This intricate and tightly regulated cellular differentiation pathway plays a crucial role in skeletal development, as cartilage serves as a fundamental component of the embryonic skele

  9. Bone collar - Wikipedia

    en.wikipedia.org/wiki/Bone_collar

    The bone collar is a cuff of periosteal bone that forms around the diaphysis of the hyaline cartilage model in developing long bones. [1] The bone collar appears during endochondral bone development to support the growing bone and help it retain its shape.