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Selenium deficiency occurs when an organism lacks the required levels of selenium, a critical nutrient in many species.Deficiency, although relatively rare in healthy well-nourished individuals, [1] can have significant negative results, [2] affecting the health of the heart and the nervous system; contributing to depression, anxiety, and dementia; and interfering with reproduction and gestation.
Selenium at nutritional levels is required for cell homeostasis, playing a role as an anti-oxidant through selenoproteins, thus, act chemo-preventive against cancer. In contrast, supra-nutritional levels act as pro-oxidant toxic in tumour cells. [39] Selenium has bimodal biological action
Selenium at nutritional levels or low concentrations is required for cell homeostasis, playing a role as an anti-oxidant through selenoproteins, thus, act chemo-preventive against cancer. In contrast, supra-nutritional levels or higher concentrations act as pro-oxidant in tumour cells, thus can be exploited as chemo-therapeutic against cancer .
It may be treated with selenium supplementation, but there is a 30–45% mortality rate. [7] Other sequelae include aspiration pneumonia, failure of passive transfer, and stunting of growth. Clinical laboratory changes include evidence of rhabdomyolysis (elevated CK and AST, myoglobinuria) and low blood selenium levels.
For this reason, Cunningham emphasizes the importance of yearly blood panels that can help identify if your symptoms warrant further investigation. Heads up: Depleted energy levels affect us all ...
There are four main types of Keshan disease: acute, subacute, chronic, and latent. Some signs and symptoms of acute Keshan disease include dizziness, malaise, nausea, chills, loss of appetite, projectile vomiting, pallor, low arterial blood pressure (less than 80/60 mmHg), dyspnea, precardiac (anterior to the heart) or substernal (behind or below the sternum) discomfort, cardiogenic shock, and ...
It also plays an important role in regulating your drive, fueling your reproductive health and allowing you to maintain stable levels of energy, healthy bones and an optimal red blood cell count.
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