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Benzamidine is a reversible competitive inhibitor of trypsin, trypsin-like enzymes, and serine proteases. [4] It is often used as a ligand in protein crystallography to prevent proteases from degrading a protein of interest. The benzamidine moiety is also found in some pharmaceuticals, such as dabigatran.
Benzamide is an organic compound with the chemical formula of C 7 H 7 NO.It is the simplest amide derivative of benzoic acid.In powdered form, it appears as a white solid, while in crystalline form, it appears as colourless crystals. [5]
Acrosin active site residues, shown with competitive inhibitor benzamidine. An important structural element of β-acrosin is a highly charged patch (formed through both amino acids and post-translational modifications) on its surface region, that has been termed the "anion binding exosite."
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In biochemistry, phenylmethylsulfonyl fluoride (PMSF) is a serine protease inhibitor (serine hydrolase inactivator) commonly used in the preparation of cell lysates.PMSF does not inactivate all serine proteases. [1]
Taking expired vitamins is generally considered safe—but there’s a catch. “Usually, expired vitamins won’t harm you, but likely will lose potency. “Usually, expired vitamins won’t harm ...
The main function of radiotherapy is to produce DNA strand breaks, causing severe DNA damage and leading to cell death. Radiotherapy has the potential to kill 100% of any targeted cells, but the dose required to do so would cause unacceptable side effects to healthy tissue.
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