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  2. Streptococcus pyogenes - Wikipedia

    en.wikipedia.org/wiki/Streptococcus_pyogenes

    S. pyogenes is the predominant species harboring the Lancefield group A antigen, and is often called group A Streptococcus (GAS). However, both Streptococcus dysgalactiae and the Streptococcus anginosus group can possess group A antigen as well.

  3. Group A streptococcal infection - Wikipedia

    en.wikipedia.org/wiki/Group_A_streptococcal...

    Group A streptococcal infections are a number of infections with Streptococcus pyogenes, a group A streptococcus (GAS). [1] S. pyogenes is a species of beta-hemolytic Gram-positive bacteria that is responsible for a wide range of infections that are mostly common and fairly mild. If the bacteria enters the bloodstream, the infection can become ...

  4. M protein (Streptococcus) - Wikipedia

    en.wikipedia.org/wiki/M_protein_(Streptococcus)

    M protein is strongly anti-phagocytic and is the major virulence factor for group A streptococci (Streptococcus pyogenes). It binds to serum factor H, destroying C3-convertase and preventing opsonization by C3b. However plasma B cells can generate antibodies against M protein which will help in opsonization and further the destruction of the ...

  5. Lancefield grouping - Wikipedia

    en.wikipedia.org/wiki/Lancefield_grouping

    Though there are many groups of streptococci, the principal organisms that are known to cause human disease belong to group A (Streptococcus pyogenes), group B (Streptococcus agalactiae), group C/G (Streptococcus dysgalactiae) both members of group D (Streptococcus gallolyticus and Streptococcus infantarius, both members of the Streptococcus ...

  6. Rapid strep test - Wikipedia

    en.wikipedia.org/wiki/Rapid_strep_test

    The rapid strep test (RST) is a rapid antigen detection test (RADT) that is widely used in clinics to assist in the diagnosis of bacterial pharyngitis caused by group A streptococci (GAS), sometimes termed strep throat. There are currently several types of rapid strep test in use, each employing a distinct technology.

  7. Streptococcal pharyngitis - Wikipedia

    en.wikipedia.org/wiki/Streptococcal_pharyngitis

    Streptococcal pharyngitis, also known as streptococcal sore throat (strep throat), is pharyngitis (an infection of the pharynx, the back of the throat) caused by Streptococcus pyogenes, a gram-positive, group A streptococcus. [9] [10] Common symptoms include fever, sore throat, red tonsils, and enlarged lymph nodes in the front of the neck.

  8. Streptolysin - Wikipedia

    en.wikipedia.org/wiki/Streptolysin

    Streptolysin O (SLO; slo), is a bacterial toxin that has four protein domains which is known to make the plasma membranes in animal cells permeable. It does this by creating pore complexes within the membrane by first binding a monomer to the cholesterol found in the target membrane and then forming an oligomeric transmembrane pore. [6]

  9. Streptococcal pyrogenic exotoxin - Wikipedia

    en.wikipedia.org/wiki/Streptococcal_pyrogenic_e...

    Streptococcal pyrogenic exotoxins also known as erythrogenic toxins, are exotoxins secreted by strains of the bacterial species Streptococcus pyogenes. [1] [2] SpeA and speC are superantigens, which induce inflammation by nonspecifically activating T cells and stimulating the production of inflammatory cytokines. [3]