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Amyl nitrites were part of some kits used to treat cyanide poisoning, containing amyl nitrite, sodium nitrite, and sodium thiosulfate. The nitrites were administered to produce methemoglobin and induce vasodilation. [40] [41] Amyl nitrites were discontinued in 2012 in standard cyanide kits. [42] Cyanide kits now use hydroxocobalamin. [43]
The term "amyl nitrite" encompasses several isomers.In older literature, the common non-systematic name amyl was often used for the pentyl group, where the amyl group is a linear or normal (n) alkyl group, and the resulting amyl nitrite would have the structural formula CH 3 (CH 2) 3 CH 2 ONO, also referred to as n-amyl nitrite.
Butyl nitrite is the organic compound with the formula CH 3 (CH 2) 3 ONO. It is an alkyl nitrite made from n-butanol.Butyl nitrite is used recreationally as poppers.Synonyms include 1-butyl nitrite, n-butyl nitrite and nitrous acid butyl ester.
Amyl nitrate is the chemical compound with the formula CH 3 (CH 2) 4 ONO 2. This molecule consists of the 5-carbon amyl group attached to a nitrate functional group . [ 1 ] It is the ester of amyl alcohol and nitric acid .
Isobutyl nitrite is one of the compounds used as poppers, an inhalant drug that induces a brief euphoria. Also, it is used as part of the antidote package for cyanide poisoning . [ medical citation needed ]
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Alkyl nitrites were initially, and largely still are, used as medications and chemical reagents, a practice which began in the late 19th century. In their use as medicine, they are often inhaled for relief of angina and other heart-related symptoms of disease. However, when referred to as "poppers", alkyl nitrites represent recreational drugs.
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