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Mannose is a sugar with the formula HOCH 2 (CHOH) 4 CHO.It is one of the monomers of the aldohexose series of carbohydrates.It is a C-2 epimer of glucose.Mannose is important in human metabolism, especially in the glycosylation of certain proteins.
In enzymology, a mannose isomerase (EC 5.3.1.7) is an enzyme that catalyzes the chemical reaction D-mannose ⇌ {\displaystyle \rightleftharpoons } D-fructose Hence, this enzyme has one substrate , D-mannose , and one product , D-fructose .
Structure of mannose in its α-D mannopyranose form. Mannan is a polymer of mannose.. The lectin pathway or MBL pathway is a type of cascade reaction in the complement system, similar in structure to the classical complement pathway, [1] in that, after activation, it proceeds through the action of C4 and C2 to produce activated complement proteins further down the cascade.
This page was last edited on 4 October 2008, at 13:37 (UTC).; Text is available under the Creative Commons Attribution-ShareAlike 4.0 License; additional terms may ...
Vaccine Excipients Adenovirus vaccine: This list refers to the type 4 and type 7 adenovirus vaccine tablets licensed in the US: Acetone, alcohol, anhydrous lactose, castor oil, cellulose acetate phthalate, dextrose, D-fructose, D-mannose, FD&C Yellow #6 aluminium lake dye, fetal bovine serum, human serum albumin, magnesium stearate, micro crystalline cellulose, plasdone C, Polacrilin potassium ...
The 3 substrates of this enzyme are GDP-D-mannose, NAD +, and H 2 O, whereas its 3 products are GDP-D-mannuronate, NADH, and H +. This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD + or NADP + as acceptor. The systematic name of this enzyme class is GDP-D-mannose:NAD + 6 ...
Since only GDP-L-gulose (the C5-epimer of GDP-D-mannose) was found in the reaction mixture, it was postulated that the enzyme performs the C5-epimerization prior to the C3-epimerization. However, GDP-D-altrose was recently found as a reaction product, which means that both reaction routes can occur: C5-prior-to-C3 and C3-prior-to-C5.
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