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Saline solution for irrigation. Normal saline (NSS, NS or N/S) is the commonly used phrase for a solution of 0.90% w/v of NaCl, 308 mOsm/L or 9.0 g per liter. Less commonly, this solution is referred to as physiological saline or isotonic saline (because it is approximately isotonic to blood serum, which makes it a physiologically normal solution).
Rapid partial correction with 3% normal saline is only recommended in those with significant symptoms and occasionally those in whom the condition was of rapid onset. [4] [6] Low volume hyponatremia is typically treated with intravenous normal saline. [4]
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The USGS salinity scale defines three levels of saline water. The salt concentration in slightly saline water is 1,000 to 3,000 ppm (0.1–0.3%); in moderately saline water is 3,000 to 10,000 ppm (0.3–1%); and in highly saline water is 10,000 to 35,000 ppm (1–3.5%).
The most commonly used crystalloid fluid is normal saline, a solution of sodium chloride at 0.9% concentration, which is close to the concentration in the blood . [3] Ringer's lactate or Ringer's acetate is another isotonic solution often used for large-volume fluid replacement.
Three types of nasal sprays preparations of sodium chloride are available including hypertonic (3% sodium chloride or sea water), isotonic (0.9% sodium chloride) and hypotonic (0.65% sodium chloride). Isotonic solutions have the same salt concentration as the human body, whereas hypertonic solutions have a higher salt content and hypotonic ...
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Thus, in term neonates, a FE Na of <3% represents volume depletion, and a FE Na as high as 4% may represent maximal sodium conservation in critically ill preterm neonates. [4] [5] The FE Na may also be spuriously elevated in children with adrenal insufficiency or pre-existing kidney disease (such as obstructive uropathy) due to salt wasting. [6]
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