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Bactrim, Bactrimel (manufactured by Roche and distributed in Europe) Bactrom (Venezuela) Bibactin (manufactured by PPM and distributed in Cambodia and some African countries) Biseptol; Sumetrolim; Co-trimoxazole (used as generic UK name) Cotrim; Deprim (AFT Pharmaceuticals) Diseptyl (Israel)
In other cases, topical is defined as applied to a localized area of the body or to the surface of a body part regardless of the location of the effect. [4] [5] By this definition, topical administration also includes transdermal application, where the substance is administered onto the skin but is absorbed into the body to attain systemic ...
Skin absorption relates to the degree of exposure to and possible effect of a substance which may enter the body through the skin. Human skin comes into contact with many agents intentionally and unintentionally. Skin absorption can occur from occupational, environmental, or consumer skin exposure to chemicals, cosmetics, or pharmaceutical ...
Figure 1.0 - Basic anatomical features of the human eye. Ophthalmic drug administration is the administration of a drug to the eyes, most typically as an eye drop formulation. Topical formulations are used to combat a multitude of diseased states of the eye. These states may include bacterial infections, eye injury, glaucoma, and dry eye. [1]
The blood–ocular barrier is a barrier created by endothelium of capillaries of the retina and iris, ciliary epithelium and retinal pigment epithelium. [1] It is a physical barrier between the local blood vessels and most parts of the eye itself, and stops many substances including drugs from traveling across it. [2]
Trimethoprim (TMP) is an antibiotic used mainly in the treatment of bladder infections. [1] Other uses include for middle ear infections and travelers' diarrhea. [1] With sulfamethoxazole or dapsone it may be used for Pneumocystis pneumonia in people with HIV/AIDS.
Eye, ear or bladder infections; usually applied directly to the eye or inhaled into the lungs; rarely given by injection, although the use of intravenous colistin is experiencing a resurgence due to the emergence of multi drug resistant organisms. Kidney and nerve damage (when given by injection)
Absorption. Sulfamethoxazole is well-absorbed when administered topically. It is rapidly absorbed when it is orally administered. [1] Distribution. Sulfamethoxazole distributes into most body tissues as well as into sputum, vaginal fluid, and middle ear fluid. [8] [11] It also crosses the placenta. About 70% of the drug is bound to plasma proteins.
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related to: where is bactrim absorbed in the human body area of the eye- 109 S High St #100, Columbus, OH · Directions · (614) 224-4261
