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Trace amine-associated receptor 1 (TAAR1) is a trace amine-associated receptor (TAAR) protein that in humans is encoded by the TAAR1 gene. [5]TAAR1 is a primarily intracellular amine-activated G s-coupled and G q-coupled G protein-coupled receptor (GPCR) that is primarily expressed in several peripheral organs and cells (e.g., the stomach, small intestine, duodenum, and white blood cells ...
RTI-7470-44 is a potent and selective antagonist of the human trace amine-associated receptor 1 (TAAR1) which is used in scientific research. [1] [2] [3] [4] It was ...
Titanium alloy in ingot form. Titanium alloys are alloys that contain a mixture of titanium and other chemical elements.Such alloys have very high tensile strength and toughness (even at extreme temperatures).
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RO5263397 is a trace amine-associated receptor 1 (TAAR1) partial agonist to full agonist. [9] [4] Its EC 50 Tooltip half-maximal effective concentration values are 0.12 to 7.5 nM for the mouse TAAR1 (mTAAR1), 35 to 47 nM for the rat TAAR1 (rTAAR1), 251 nM at the cynomolgus monkey TAAR1, and 17 to 85 nM for the human TAAR1 (hTAAR1).
Download as PDF; Printable version; In other projects Wikidata item; Appearance. move to sidebar hide. Pharmacodynamics of amphetamine in a dopamine neuron ...
Trace amines are an endogenous group of trace amine-associated receptor 1 (TAAR1) agonists [1] – and hence, monoaminergic neuromodulators [2] [3] [4] – that are structurally and metabolically related to classical monoamine neurotransmitters. [5]