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Intestinal malrotation is a congenital anomaly of rotation of the midgut. It occurs during the first trimester as the fetal gut undergoes a complex series of growth and development. Malrotation can lead to a dangerous complication called volvulus, in which cases emergency surgery is indicated. [1]
The small intestine forms loops (B2) and slides back into the abdomen (B3) during resolution of the hernia. Meanwhile, the cecum moves from the left to the right side, which represents the additional 180° counterclockwise rotation of the intestine (C, central view). [3] In the process of lengthening growth, the intestinal duct herniates and ...
In the human embryo, the vitelline duct, also known as the vitellointestinal duct, [1] the yolk stalk, [1] the omphaloenteric duct, [1] or the omphalomesenteric duct, [1] is a long narrow tube that joins the yolk sac to the midgut lumen of the developing fetus. [2]
Gastric volvulus or volvulus of stomach is a twisting of all or part of the stomach by more than 180 degrees with obstruction of the flow of material through the stomach, variable loss of blood supply and possible tissue death. The twisting can occur around the long axis of the stomach, called organoaxial, or around the axis perpendicular to ...
This rotation also affects the part of the gastrointestinal tube immediately below the stomach, which will go on to become the duodenum. By the end of the fourth week, the developing duodenum begins to spout a small outpouching on its right side, the hepatic diverticulum , which will go on to become the biliary tree .
The stomach can also be affected. [6] Diagnosis is typically with medical imaging such as plain X-rays, a GI series, or CT scan. [1] Initial treatment for sigmoid volvulus may occasionally occur via sigmoidoscopy or with a barium enema. [3] Due to the high risk of recurrence, a bowel resection within the next two days is generally recommended. [3]
There are several examples of symmetry breaking that are currently being studied. One of the most studied examples is the cortical rotation during Xenopus development, where this rotation acts as the symmetry-breaking event that determines the dorsal-ventral axis of the developing embryo. This example is discussed in more detail below.
The initial stomach differentiation begins. [5] This embryo is also from an ectopic pregnancy, this one in the cornu (the part of the uterus to which the Fallopian tube is attached). The features are consistent with a developmental age of seven weeks (reckoned as the ninth week of pregnancy).