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2. Anti-amyloid drugs - Wikipedia

   en.wikipedia.org/wiki/Anti-amyloid_drugs

   Aducanumab, sold under the brand name Aduhelm, is a monoclonal antibody designed to treat Alzheimer's disease. It is a monoclonal antibody that targets aggregated forms (plaque) of amyloid beta (Aβ) found in the brains of people with Alzheimer's disease to reduce its buildup. [10] It was developed by Biogen and Eisai. [11] Aducanumab is given via intravenous infusion. [5] Aducanumab was ...

3. Eplontersen - Wikipedia

   en.wikipedia.org/wiki/Eplontersen

   Eplontersen, sold under the brand name Wainua, is a medication used for the treatment of transthyretin-mediated amyloidosis. [3] It is a transthyretin-directed antisense oligonucleotide. [3]

4. U.S. approves Alzheimer's drug that modestly slows disease - AOL

   www.aol.com/news/alzheimers-drug-modestly-slows...

   The Food and Drug Administration approved it for patients with Alzheimer's, specifically those with mild or early-stage disease. ... Leqembi works by clearing a sticky brain protein called amyloid ...

5. A Revolutionary New Alzheimer’s Drug Was Just Approved by the ...

   www.aol.com/revolutionary-alzheimer-drug-just...

   Lecanemab (a.k.a. Leqembi) is the first amyloid beta-directed antibody to be converted from an accelerated approval to a traditional approval for the treatment of Alzheimer’s disease, the FDA ...

6. Solanezumab - Wikipedia

   en.wikipedia.org/wiki/Solanezumab

   Solanezumab binds the amyloid-β peptides that aggregate and form plaques in the brain that are an early pathological feature of Alzheimer's disease. [11] Solanezumab binds the central epitope of monomeric amyloid-β, KLVFFAED, (PDB ID 4XXD [12]) with picomolar affinity. [13]

7. How a new FDA-approved drug can — and can’t — help people ...

   www.aol.com/lifestyle/fda-approved-drug-t-help...

   In early 2023, the U.S. Food and Drug Administration (FDA) granted accelerated approval to a new Alzheimer’s drug called Leqembi. ... Amyloid plaque is a substance that may lead to tissue loss ...

8. Eli Lilly Alzheimer's drug approved by US FDA - AOL

   www.aol.com/news/us-fda-approves-lillys...

   A key differentiating factor for donanemab is the drug's finite dosing, which allows patients to stop taking the treatment once brain scans no longer show amyloid plaques. Lilly priced its drug at ...

9. Amyloid beta - Wikipedia

   en.wikipedia.org/wiki/Amyloid_beta

   Amyloid beta (Aβ, Abeta or beta-amyloid) denotes peptides of 36–43 amino acids that are the main component of the amyloid plaques found in the brains of people with Alzheimer's disease. [2] The peptides derive from the amyloid-beta precursor protein (APP), which is cleaved by beta secretase and gamma secretase to yield Aβ in a cholesterol ...