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Granuloma; Picture of a granuloma (without necrosis) as seen through a microscope on a glass slide: The tissue on the slide is stained with two standard dyes (hematoxylin: blue, eosin: pink) to make it visible. The granuloma in this picture was found in a lymph node of a patient with a Mycobacterium avium infection. Specialty: Pathology
SCC of the skin begins as a small nodule and as it enlarges the center becomes necrotic and sloughs and the nodule turns into an ulcer, and generally are developed from an actinic keratosis. Once keratinocytes begin to grow uncontrollably, they have the potential to become cancerous and produce cutaneous squamous-cell carcinoma. [22]
Histopathologic image of granular cell tumor of the skin Granular cell tumor is a tumor that can develop on any skin or mucosal surface, but occurs on the tongue 40% of the time. It is also known as Abrikossoff's tumor , [ 1 ] granular cell myoblastoma , [ 1 ] granular cell nerve sheath tumor , [ 1 ] and granular cell schwannoma . [ 1 ]
[9] commonly presents as a painless, red and brown or red and yellow, ulcerated papule on the head or neck and may mimic nonmelanoma skin cancers, molluscum contagiosum, adnexal neoplasms, or pyogenic granuloma. [2] [6] The mean lesion size of periocular and extraocular SGc is approximately 1.4 cm. [2]
The skin weighs an average of four kilograms, covers an area of two square metres, and is made of three distinct layers: the epidermis, dermis, and subcutaneous tissue. [1] The two main types of human skin are: glabrous skin, the hairless skin on the palms and soles (also referred to as the "palmoplantar" surfaces), and hair-bearing skin. [3]
When actinic granuloma-like lesions appear in non-exposed areas, the rash is known as annular elastolytic giant cell granuloma. Though these can be easily distinguished based on histopathologic features and laboratory findings, the differential diagnosis includes tinea corporis , sarcoidosis , subacute lupus erythematosus , granuloma annulare ...
Lymphomatoid granulomatosis (LYG or LG) is a very rare lymphoproliferative disorder first characterized in 1972. [1] Lymphomatoid means lymphoma-like and granulomatosis denotes the microscopic characteristic of the presence of granulomas with polymorphic lymphoid infiltrates and focal necrosis within it.
Skin cancer is the most common form of cancer, globally accounting for at least 40% of cancer cases. [5] [20] The most common type is nonmelanoma skin cancer, which occurs in at least 2–3 million people per year. [6] [21] This is a rough estimate; good statistics are not kept. [1]