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Because clonazepam is effective in low milligram doses (0.5 mg clonazepam = 10 mg diazepam), [118] [119] it is said to be among the class of "highly potent" benzodiazepines. [120] The anticonvulsant properties of benzodiazepines are due to the enhancement of synaptic GABA responses, and the inhibition of sustained, high-frequency repetitive firing.
Clonazepam, a benzodiazepine is used to treat many forms of parasomnia. [77] Rapid eye movement behavior disorder responds well to low doses of clonazepam. [78] [79] Restless legs syndrome can be treated using clonazepam as a third line treatment option as the use of clonazepam is still investigational. [80] [81]
Cloniprazepam is a benzodiazepine derivative and a prodrug of clonazepam, 7-aminoclonazepam, and other metabolites. [ 1 ] [ 2 ] Some of the minor metabolites include 3-hydroxyclonazepam and 6-hydroxyclonazepam , 3-hydroxycloniprazepam and ketocloniprazepam with ketone group formed where 3-hydroxy group was.
Here are links to possibly useful sources of information about Clonazepam. PubMed provides review articles from the past five years (limit to free review articles) The TRIP database provides clinical publications about evidence-based medicine. Other potential sources include: Centre for Reviews and Dissemination and CDC
Starting in 2010, every year free books are distributed to students between Grade-1 to Grade-10 to eliminate illiteracy. [6] These books comprise most of the curricula of the majority of Bangladeshi schools. There are two versions of the curriculum. One is the Bengali language version and the other one is English language version.
Clonazolam's effects are similar to other benzodiazepines, such as anxiolysis, disinhibition, lethargy, muscle relaxation, and euphoria. [2] [8] While no dose of clonazolam is considered "safe" due to its lack of research and extreme potency, doses higher than 0.5 mg can cause benzodiazepine overdose in some individuals.
Clorazepate is a "classical" benzodiazepine. Other classical benzodiazepines include chlordiazepoxide, diazepam, clonazepam, oxazepam, lorazepam, nitrazepam, bromazepam and flurazepam. [13] Clorazepate is a long-acting benzodiazepine drug. [10]
The directorate is under the Ministry of Cultural Affairs [4] The government of Bangladesh provided the library with air conditioning in 1978, under the government's five-year plan. In 2008 the library was without electricity for about a month because of the Dhaka Electric Supply Company and the Public Works Department refused to fix it. [ 6 ]
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