Search results
Results from the WOW.Com Content Network
The concept of additive effect is analogous to the concept of simple addition in mathematics. However, the additive effect is not simply the arithmetic summation of two (or more) drugs in most cases. [20] For an additive inhibition effect, drug A and drug B could each inhibit 20% individually, but the additive effect is not 40%.
In general, the safety and effectiveness of alternative medicines have not been scientifically proven [1] and remain largely unknown. [2] Beyond adverse effects from the herb itself, "adulteration, inappropriate formulation , or lack of understanding of plant and drug interactions have led to adverse reactions that are sometimes life ...
Acceptable daily intake or ADI is a measure of the amount of a specific substance (originally applied for a food additive, later also for a residue of a veterinary drug or pesticide) in food or drinking water that can be ingested (orally) daily over a lifetime without an appreciable health risk. [1]
The Food and Drug Administration ... “Revoking the authorized use of Red No. 3 is an example of the FDA using its risk and science-based authority to review the safety of products in the ...
Adverse human health effects have been associated with a compound. There is an established relationship between the positive and negative effect(s) of the compound. Emerging contaminants are those which have not previously been detected through water quality analysis, or have been found in small concentrations with uncertainty as to their effects.
A popular example of drug–food interaction is the effect of grapefruit on the metabolism of drugs. Interactions may occur by simultaneous targeting of receptors , directly or indirectly. For example, both Zolpidem and alcohol affect GABA A receptors , and their simultaneous consumption results in the overstimulation of the receptor, which can ...
Adverse effects, like therapeutic effects of drugs, are a function of dosage or drug levels at the target organs, so they may be avoided or decreased by means of careful and precise pharmacokinetics, the change of drug levels in the organism in function of time after administration. Adverse effects may also be caused by drug interaction. This ...
The artificial sweetener aspartame has been the subject of several controversies since its initial approval by the U.S. Food and Drug Administration (FDA) in 1974. The FDA approval of aspartame was highly contested, beginning with suspicions of its involvement in brain cancer, [1] alleging that the quality of the initial research supporting its safety was inadequate and flawed, and that ...