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In 1993 the first C57BL/6 gene targeted knockout mouse was published by a group at Hoffmann-La Roche in Switzerland. [10] In 2013 C57BL/6 mice were flown into space aboard Bion-M No.1. [11] In 2015 C57BL/6NTac females provided by Taconic Biosciences were sent to the International Space Station on SpaceX CRS-6. [12]
Autosomal dominant and autosomal recessive inheritance, the two most common Mendelian inheritance patterns. An autosome is any chromosome other than a sex chromosome.. In genetics, dominance is the phenomenon of one variant of a gene on a chromosome masking or overriding the effect of a different variant of the same gene on the other copy of the chromosome.
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Autosomal dominant pedigree chart. In Autosomal Dominance the chance of receiving and expressing a particular gene is 50% regardless of the sex of parent or child. Date: 22 July 2006: Source: Own work: Author: Jerome Walker: Permission (Reusing this file)
Figure 1: Inheritance pattern of dominant (red) and recessive (white) phenotypes when each parent (1) is homozygous for either the dominant or recessive trait. All members of the F 1 generation are heterozygous and share the same dominant phenotype (2), while the F 2 generation exhibits a 6:2 ratio of dominant to recessive phenotypes (3).
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3.In this model, blue organisms express the recessive mendelian genes. This is an example of a sperm from a haploid individual carrying the recessive genes. 4.This is a sperm from a diploid individual that is carrying a recessive gene for a blue color. 5.This is a egg from a diploid individual that is carrying a dominant gene for a purple color.