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  2. Vitamin K deficiency - Wikipedia

    en.wikipedia.org/wiki/Vitamin_K_deficiency

    Symptoms include bruising, [2] petechiae, [2] [3] and hematomas.. Vitamin K is changed to its active form in the liver by the enzyme Vitamin K epoxide reductase.Activated vitamin K is then used to gamma carboxylate (and thus activate) certain enzymes involved in coagulation: Factors II, VII, IX, X, and protein C and protein S.

  3. Calcification - Wikipedia

    en.wikipedia.org/wiki/Calcification

    Calcification is the accumulation of calcium salts in a body tissue. It normally occurs in the formation of bone, but calcium can be deposited abnormally in soft tissue, [1] [2] causing it to harden. Calcifications may be classified on whether there is mineral balance or not, and the location of the calcification. [3]

  4. Lysosomal acid lipase deficiency - Wikipedia

    en.wikipedia.org/wiki/Lysosomal_acid_lipase...

    An ultrasound examination shows an accumulation of chalky material (calcification) in the adrenal gland in about half of infants with LAL-D. [2] [4] Complications of LAL-D progress over time, eventually leading to life-threatening problems such as extremely low levels of circulating red blood cells (severe anemia), liver dysfunction or failure ...

  5. Hypervitaminosis A - Wikipedia

    en.wikipedia.org/wiki/Hypervitaminosis_A

    Diet – Liver is high in vitamin A. The liver of certain animals, including the polar bear, bearded seal, [25] [26] fish and [27] walrus, [28] are particularly toxic (see Liver (food) § Poisoning). It has been estimated that consumption of 500 grams (18 oz) of polar bear liver would result in a toxic dose for a human. [25]

  6. Hypercalcaemia - Wikipedia

    en.wikipedia.org/wiki/Hypercalcaemia

    Calcium deposits known as limbus sign may be visible in the eyes. [7] Symptoms are more common at high calcium blood values (12.0 mg/dL or 3 mmol/L). [6] Severe hypercalcaemia (above 15–16 mg/dL or 3.75–4 mmol/L) is considered a medical emergency: at these levels, coma and cardiac arrest can result.

  7. Calciphylaxis - Wikipedia

    en.wikipedia.org/wiki/Calciphylaxis

    Calciphylaxis, also known as calcific uremic arteriolopathy (CUA) or “Grey Scale”, is a rare syndrome characterized by painful skin lesions.The pathogenesis of calciphylaxis is unclear but believed to involve calcification of the small blood vessels located within the fatty tissue and deeper layers of the skin, blood clots, and eventual death of skin cells due to lack of blood flow. [1]

  8. Dystrophic calcification - Wikipedia

    en.wikipedia.org/wiki/Dystrophic_calcification

    Dystrophic calcification (DC) is the calcification occurring in degenerated or necrotic tissue, as in hyalinized scars, degenerated foci in leiomyomas, and caseous nodules. This occurs as a reaction to tissue damage, [ 1 ] including as a consequence of medical device implantation.

  9. Liver failure - Wikipedia

    en.wikipedia.org/wiki/Liver_failure

    Liver failure is the inability of the liver to perform its normal synthetic and metabolic functions as part of normal physiology. Two forms are recognised, acute and chronic (cirrhosis). [ 1 ] Recently, a third form of liver failure known as acute-on-chronic liver failure ( ACLF ) is increasingly being recognized.

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