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  2. Experimental treatment pushed by ALS patients gets day ... - AOL

    www.aol.com/news/experimental-treatment-pushed...

    NurOwn is the clearest test yet of how far the agency may be willing to bend to approve a new medicine for a rare and deadly condition with few treatment options. ALS gradually destroys nerve ...

  3. New treatment may slow ALS, with help from Ice Bucket ... - AOL

    www.aol.com/treatment-may-slow-als-help...

    An experimental medication may slow the progression of amyotrophic lateral sclerosis, or ALS, researchers reported Wednesday. The research was supported in part by donations from the Ice Bucket ...

  4. Breakthrough therapy - Wikipedia

    en.wikipedia.org/wiki/Breakthrough_therapy

    A breakthrough therapy designation can be assigned to a drug if "it is a drug which is intended alone or in combination with one or more other drugs to treat a serious or life threatening disease or condition" and if the preliminary clinical evidence indicates that the drug may demonstrate substantial improvement over existing therapies on one or more clinically significant endpoints, such as ...

  5. FDA advisers vote against experimental ALS treatment ... - AOL

    www.aol.com/news/fda-advisers-vote-against...

    Federal health advisers voted overwhelmingly against an experimental treatment for Lou Gehrig’s disease at a Wednesday meeting prompted by years of patient efforts seeking access to the unproven ...

  6. List of drugs granted breakthrough therapy designation

    en.wikipedia.org/wiki/List_of_drugs_granted...

    Treatment of people aged twelve years of age and older with solid tumors that: have a neurotrophic tyrosine receptor kinase (NTRK) gene fusion, are locally advanced or metastatic or where surgical resection is likely to result in severe morbidity, and have progressed following treatment or have no satisfactory alternative therapy [2]

  7. ALS Therapy Development Institute - Wikipedia

    en.wikipedia.org/wiki/ALS_Therapy_Development...

    The institute has raised and spent more than $100 million on research into effective treatments for ALS and practices open-source science. [19] After the discovery that the multiple sclerosis drug Gilenya might also be a treatment for ALS, the Institute enrolled 30 people in a Phase 2A clinical trial the drug in 2013, though it did not progress further.

  8. Amyotrophic lateral sclerosis research - Wikipedia

    en.wikipedia.org/wiki/Amyotrophic_lateral...

    In this study the researcher can isolate skin fibroblast from a patient with familial or sporadic ALS and reprogram them into motor neuron to study ALS. [2] The main advantage of iPSC is that it allowed researchers to study and understand sALS, and it shows a remarkable contribution in cell-based therapy and drug screening. [ 2 ]

  9. Firefighter with ALS to Join Friend In Stem Cell Treatment - AOL

    www.aol.com/news/firefighter-als-join-friend...

    An Arkansas firefighter is undergoing a new treatment for ALS with a friend to support each other along the way.

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