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Ezetimibe/atorvastatin (trade names Liptruzet, Atozet) is a cholesterol lowering combination drug. In the United States, it was approved in May 2013, by the Food and Drug Administration for the treatment of elevated low-density lipoprotein (LDL) in patients with primary or mixed hyperlipidemia as adjunctive therapy to diet. [ 1 ]
Daflon is an oral micronized purified phlebotonic flavonoid fraction containing 90% diosmin and 10% hesperidin.It is manufactured by Laboratoires Servier and often used to treat or manage disorders of the blood vessels.
Duration of treatment with atorvastatin is unlikely to increase the risk of muscle-related side effects as most occur within the first year of treatment, after which the risk is not increased further. [64] The known cardiovascular benefits of atorvastatin over time outweigh the low risk of muscle-related side effects. [65] [64]
The three flavonoid classes above are all ketone-containing compounds and as such, anthoxanthins (flavones and flavonols). [1] This class was the first to be termed bioflavonoids. The terms flavonoid and bioflavonoid have also been more loosely used to describe non-ketone polyhydroxy polyphenol compounds, which are more specifically termed ...
A 2013 Cochrane review found a decrease in risk of death and other poor outcomes without any evidence of harm. [4] For every 138 people treated for 5 years, one fewer dies; for every 49 treated, one fewer has an episode of heart disease. [11] A 2011 review reached similar conclusions, [25] and a 2012 review found benefits in both women and men ...
The FDA also urged consumers to avoid purchasing fat-dissolving products from websites, noting that the products might be ineffective and may carry a risk of severe side effects.
More than 260 medications have been reported to cause tinnitus as a side effect. [41] Tinnitus can also occur from the discontinuation of therapeutic doses of benzodiazepines. It can sometimes be a protracted symptom of benzodiazepine withdrawal and may persist for many months. [42] [43] Medications such as bupropion may also cause tinnitus. [44]
The annoyance of tinnitus also tends to decline over time. In some people, tinnitus spontaneously disappears. [1] A Cochrane review found only one sufficiently rigorous study of TRT and noted that while the study suggested benefit in the treatment of tinnitus, the study quality was not good enough to draw firm conclusions. [5]
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