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Left untreated, it has a mortality rate of 8% to 58%, with a greater death rate among males. [3] The symptoms of syphilis have become less severe over the 19th and 20th centuries, in part due to widespread availability of effective treatment, and partly due to virulence of the bacteria. [23] With early treatment, few complications result. [22]
Untreated, it can lead to complications and death. [67] Clinical manifestations of syphilis include the ulceration of the uro-genital tract, mouth or rectum; if left untreated the symptoms worsen. In recent years, the prevalence of syphilis has declined in Western Europe, but it has increased in Eastern Europe (former Soviet states).
Tabes dorsalis is caused by demyelination by advanced syphilis infection (tertiary syphilis) when the primary infection by the causative spirochete bacterium, Treponema pallidum, is left untreated for an extended period of time (past the point of blood infection by the organism). [3]
Congenital syphilis is syphilis that occurs when a mother with untreated syphilis passes the infection to her baby during pregnancy or at birth. [4] It may present in the fetus, infant, or later. [1] [5] Clinical features vary and differ between early onset, that is presentation before 2-years of age, and late onset, presentation after age 2 ...
What are the symptoms of ocular syphilis? When syphilis affects the eyes, it usually causes inflammation inside them known as uveitis , Khurana says. Eyes may be red, light sensitive or painful ...
Public health officials in Chicago say they have been seeing a worrisome trend: Patients complaining of unusual symptoms like vision and eye problems, headaches, and hearing loss or dizziness ...
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Neurosyphilis is the infection of the central nervous system by Treponema pallidum, the bacterium that causes the sexually transmitted infection syphilis.In the era of modern antibiotics, the majority of neurosyphilis cases have been reported in HIV-infected patients.