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Although meropenem is not approved for intramuscular or subcutaneous routes of administration in humans, there were studies that evaluated the drug bioavailability in cats and reported bioavailability of 99.69% for intramuscular route and 96.52 % for subcutaneous route of administration; these studies also compared elimination half-lives for ...
Meropenem works by blocking the construction of the bacterial cell wall while vaborbactam blocks the breakdown of meropenem by some beta-lactamases. [ 4 ] The combination was approved for medical use in the United States in 2017, [ 6 ] in the European Union in 2018, [ 4 ] [ 3 ] and in Canada in December 2024. [ 1 ]
The β-lactam core structures. (A) A penam.(B) A carbapenam.(C) An oxapenam.(D) A penem.(E) A carbapenem.(F) A monobactam.(G) A cephem.(H) A carbacephem.(I) An oxacephem. This is a list of common β-lactam antibiotics—both administered drugs and those not in clinical use—organized by structural class.
A systematic review performed by an employee of the company that markets meropenem concluded that it provides a higher bacterial response and lower adverse event rates than imipenem in people with severe infections, but no difference in mortality rate. [25] Ertapenem is administered once daily as an intravenous infusion or intramuscular injection.
Meropenem, an antibiotic initially marketed under the trade name Merrem Blasius Merrem (1761–1824), German naturalist, zoologist, ornithologist, mathematician, and herpetologist Topics referred to by the same term
The most common form of sterilization in dogs and cats is surgical, spaying in females and castration in males. Non-surgical fertility control can either result in sterilization or temporary contraception and could offer a cheaper way to keep wild dog and cat populations under control. As of 2019, only contraceptives are commercially available.
A 2008 review of 42 studies of in vitro susceptibility of bacteria to tigecycline showed that MDR K. pneumoniae and E. coli, including those that were carbapenem resistant, were susceptible more than 90% of the time. A limited number of patients have been treated with tigecycline, but the FDA has approved it in certain cases with synergies of ...
The first recalls were announced by Menu Foods late on Friday, 16 March 2007, for cat and dog food products in the United States. In the ensuing months, many additional recalls were announced by Menu and other companies as the recall expanded throughout North America and to Europe and South Africa.
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